Results 111 to 120 of about 820,585 (334)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Inelastic aluminium-hydrogen collision data for non-LTE applications in stellar atmospheres

, 2013
Aims. Inelastic processes in low-energy Si + H and Si+ + H- collisions are treated for the states from the ground state up to the ionic state, in order to provide rate coefficients needed for non-LTE modeling of Si in cool stellar atmospheres.
A. K. Belyaev
semanticscholar   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

Observations of the Ultraviolet-bright Star III-60 in the Globular Cluster NGC 6723

The Astrophysical Journal
We have analyzed archival far-ultraviolet spectra of the UV-bright star III-60 in the globular cluster NGC 6723 obtained with the Far Ultraviolet Spectroscopic Explorer and the Cosmic Origins Spectrograph. We find that the star's photospheric parameters (
William V. Dixon
doaj   +1 more source

Physics of Stellar Atmospheres [PDF]

Nature, 1956
Physik der Sternatmospharen, mit besonderer Berucksichtigung der Sonne Zweite Auflage. Von Prof. A. Unsold. Pp. ix + 866. (Berlin: Springer-Verlag, 1955.) 168 D.M.
openaire   +2 more sources

Profiling the effect of low frequency mechanical vibration on the metabolic and oxidative stress responses of A431 carcinoma

FEBS Open Bio, EarlyView.
20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti, Chikahiro Imashiro, Takashi Morikura, Shogo Miyata, Akira Funahashi, Kenjiro Takemura   +5 more
wiley   +1 more source

Population-level Hypothesis Testing with Rocky Planet Emission Data: A Tentative Trend in the Brightness Temperatures of M-Earths

The Astrophysical Journal
Determining which rocky exoplanets have atmospheres, and why, is a key goal for the James Webb Space Telescope. So far, emission observations of individual rocky exoplanets orbiting M stars (M-Earths) have not provided definitive evidence for atmospheres.
Brandon Park Coy, Jegug Ih, Edwin S. Kite, Daniel D. B. Koll, Moritz Tenthoff, Jacob L. Bean, Megan Weiner Mansfield, Michael Zhang, Qiao Xue, Eliza M.-R. Kempton, Kay Wohlfarth, Renyu Hu, Xintong Lyu, Christian Wöhler   +13 more
doaj   +1 more source

A Variational Method for Improving Model Stellar Atmospheres [PDF]

, 1955
A. Przybylski
openalex   +1 more source

GDP‐fucose transporter SLC35C1: a potential regulatory role in cytosolic GDP‐fucose and fucosylated glycan synthesis

FEBS Open Bio, EarlyView.
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley   +1 more source