Results 51 to 60 of about 239 (207)

Streams and Bubbles: Tidal Shaping of Hydrodynamic Planetary Outflows

The Astrophysical Journal
Planets, especially those close to their host stars, lose mass to atmospheric outflows, a process that is thought to shape the bimodal population of gaseous giant and rocky terrestrial exoplanets in close orbits.
Morgan MacLeod, Antonija Oklopčić, Fabienne Nail, Dion Linssen   +3 more
doaj   +1 more source

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

Advanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li, Xijia Wang, Yaning Hu, Zhen Yang, Tian Niu, Xingbo Zhao   +5 more
wiley   +1 more source

Interstellar Ultraviolet Lyα High Resolution Mapping from the New Horizons P-Alice Instrument

The Astronomical Journal
We present New Horizons Alice spectral observations of interstellar hydrogen Ly α emissions at a vantage point of 57 au from the Sun. The observations were conducted as a pair of orthogonal scans to produce high spatial angular resolution measurements of
Tracy M. Becker, G. Randall Gladstone, Joel Wm. Parker, J. Michael Shull, Seth Redfield, Sarah Ruetschle, Nathaniel J. Cunningham, Cynthia S. Froning, Joshua A. Kammer, John R. Spencer, Marc Postman, Tod R. Lauer, Jayant Murthy, Maarten H. Versteeg, Jon P. Pineau, Kurt D. Retherford, Anne J. Verbiscer, Pontus C. Brandt, Kelsi N. Singer, S. Alan Stern   +19 more
doaj   +1 more source

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

Radiation hydrodynamics of star-disc collisions for quasi-periodic eruptions

Astronomy & Astrophysics
Context. Quasi-periodic eruptions (QPEs) are recently discovered transients of an unknown nature that occur near supermassive black holes and feature bright X-ray bursts separated by hours to days.
Jankovič T., Bonnerot C., Karpov S., Jurca A.   +3 more
doaj   +1 more source

Palmitoylation of PSD‐95 Orchestrates Learning‐Dependent Metaplasticity in the Amygdala and Fear Memory

Advanced Science, EarlyView.
This study reveals that fear learning specifically triggers PICK1/DHHC2‐dependent palmitoylation of PSD‐95 in the lateral amygdala. Fear conditioning induces the dissociation of DHHC5 from PSD‐95 and the association of PSD‐95 with DHHC2. DHHC2‐mediated palmitoylation of PSD‐95 is required for synaptic transmission and underlies fear learning–induced ...
Zu‐Cheng Shen, Yu‐Xuan Weng, Zhi‐Xuan Xia, Yue‐Ling Zhao, Qian‐Qian Ding, Si‐Ying Wang, Ting Cao, Xuan‐Ying Chen, Wu‐Cheng Tao, Shen Lin, Zhou Chen, Yi‐Xiao Luo   +11 more
wiley   +1 more source

Velocity-resolved [O I] 63 145 µm, [C II] 158 µm, and OH mapping along the Orion BN/KL explosive outflow and irradiated shocks★

Astronomy & Astrophysics
Stellar mergers produce “explosive outflows” that serve as transient sources of infrared line luminosity and inject mechanical energy early into the natal molecular cloud. We present the first velocity-resolved, sub-km s−1 resolution maps of the [O I] 63
Goicoechea Javier R., Güsten Rolf, Godard Benjamin, Wiesemeyer Helmut, Higgins Ronan, Gusdorf Antoine, Santa-Maria Miriam G., Zannese Marion, Menten Karl M.   +8 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Molecular and Cellular Hallmarks of Age‐Related Vestibular Hair Cell Degeneration

Advanced Science, EarlyView.
This study utilizes single‐cell RNA‐seq transcriptomes, advanced imaging, and electrophysiology to examine universal and cell‐type‐specific aging signatures of vestibular hair cells. The study shows that impaired hair bundle function is a key driver of age‐related vestibular dysfunction.
Samadhi Kulasooriya, Huizhan Liu, Sarath Vijayakumar, Celia Bloom, Zhenhang Xu, Shu Tu, Benjamin J. Borgmeier, Mi Zhou, Litao Tao, Bechara Kachar, David Z. He   +10 more
wiley   +1 more source

The Inner and Outer Shock Layers of Bow Shocks in Cataclysmic Variables

The Astrophysical Journal Letters
Bow shocks around cataclysmic variables (CVs) have traditionally been identified with a single bright optical arc. This feature has been interpreted as the bow shock formed by the interaction between a sustained outflow and the interstellar medium (ISM).
Krystian Iłkiewicz, Christian Knigge, Simone Scaringi, Noel Castro Segura, Santiago del Palacio, Martina Veresvarska   +5 more
doaj   +1 more source