Results 141 to 150 of about 2,514,308 (344)

THE K2 ECLIPTIC PLANE INPUT CATALOG (EPIC) AND STELLAR CLASSIFICATIONS OF 138,600 TARGETS IN CAMPAIGNS 1–8 [PDF]

open access: green, 2016
Daniel Huber   +8 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Red Stellar Populations and Dust Extinction toward W3

open access: yesThe Astrophysical Journal
We explore red stellar populations toward the W3 giant molecular cloud through the use of optical-to-infrared (IR) photometry and Gaia DR 3 data, simultaneously characterizing stellar content and properties of dust in the molecular medium.
J. L. Campbell   +4 more
doaj   +1 more source

Analysis of Habitability and Stellar Habitable Zones from Observed Exoplanets

open access: yesGalaxies
The investigation of exoplanetary habitability is integral to advancing our knowledge of extraterrestrial life potential and detailing the environmental conditions of distant worlds. In this analysis, we explore the properties of exoplanets situated with
Jonathan H. Jiang   +4 more
doaj   +1 more source

III.5 Stellar classification in CoRoT faint stars fields

open access: gold, 2020
C. Damiani   +4 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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