Results 41 to 50 of about 153,316 (253)

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Astroparticles from X-Ray Binary Coronae

The Astrophysical Journal Letters
The recent observation of high-energy neutrinos from the Galactic plane implies an abundant population of hadronic cosmic-ray sources in the Milky Way.
K. Fang, Francis Halzen, Sebastian Heinz, John S. Gallagher   +3 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

High-velocity Blue-shifted Fe xxv Heα Line during a Superflare of the RS Canum Venaticorum–type Star IM Peg

The Astrophysical Journal Letters
The Monitor of All-sky X-ray Image (MAXI) detected a superflare, releasing 5 × 10 ^37 erg in 2−10 keV, of the RS CVn-type star IM Peg at 10:41 UT on 2023 July 23 with its Gas Slit Camera (2−30 keV).
Shun Inoue, Wataru Buz Iwakiri, Teruaki Enoto, Hiroyuki Uchida, Miki Kurihara, Masahiro Tsujimoto, Yuta Notsu, Kenji Hamaguchi, Keith Gendreau, Zaven Arzoumanian, Takeshi Go Tsuru   +10 more
doaj   +1 more source

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian, Tianjia Zhu, Hao Huang, Shavonne L. Massey, Mark P. Fitzgerald, Darshana Parikh, Arastoo Vossough, Ingo Helbig, Nicholas S. Abend   +8 more
wiley   +1 more source

High-resolution Modeling of Coronae and Winds in Solar-type Stars with Varying Rotation Rates. II. Stellar Winds

The Astrophysical Journal
Observations suggest a connection between steady-wind mass loss and coronal X-ray activity in low-mass main-sequence stars. Interpreting this connection is challenging because the wind is controlled mainly by the large-scale open field, whereas X-ray ...
Yue-Hong Chen, Julián D. Alvarado-Gómez, Xin Cheng, Victor See, Yu Dai, Maarit J. Korpi-Lagg, Jörn Warnecke, Chen Xing, Mingde Ding   +8 more
doaj   +1 more source

Magnetohydrodynamic seismology of solar and stellar coronae

, 2008
The review presents the study of long period (longer than a few seconds) wave and oscillation phenomena in the corona of the Sun in radio, VL, EUV and X-ray bands, interpreted in terms of MHD theory.
Nakariakov, V. M. (Valery M.)
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

The Stagger Code for Accurate and Efficient, Radiation-coupled Magnetohydrodynamic Simulations

The Astrophysical Journal
We describe the Stagger code for simulations of magnetohydrodynamic (MHD) systems. This is a modular code with a variety of physics modules that will let the user run simulations of deep stellar atmospheres, sunspot formation, stellar chromospheres and ...
Robert F. Stein, Åke Nordlund, Remo Collet, Regner Trampedach   +3 more
doaj   +1 more source

X-ray astronomy of stellar coronae [PDF]

, 2018
.: X-ray emission from stars in the cool half of the Hertzsprung-Russell diagram is generally attributed to the presence of a magnetic corona that contains plasma at temperatures exceeding 1 million K.
Güdel, Manuel
core