Results 71 to 80 of about 276 (256)

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Role of Nonthermal Processes in the Quiescent and Active Millimeter Spectrum of a Young M Dwarf

The Astrophysical Journal
Millimeter (mm) emission from F-M dwarfs (cool stars) primarily traces chromospheric activity, with thermal emission thought to dominate in quiescence. Despite the high chromospheric activity, the quiescent mm spectral fluence (mm- S ( ν )) of young (1 ...
Atul Mohan, Peter H. Hauschildt, Birgit Fuhrmeister, Surajit Mondal, Vladimir Airapetian, Sven Wedemeyer   +5 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Nanomaterial Strategies for Pulmonary Delivery of Immunotherapeutics in Lung Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Inhalable immunotherapeutic nanomedicines enable organ‐selective immune modulation by overcoming pulmonary delivery barriers and concentrating therapy within lung tumors. This Review defines how nanomaterial properties govern airway deposition, retention, cellular partitioning, and immune activation across vaccines, checkpoint blockade, STING agonists,
Han Zhang, Wei Tang
wiley   +1 more source

Summary of the First Year of the Space Weather Around Young Suns Program: 900 hr of Low-frequency Radio and Optical Data Dedicated to Young, Solar-type Stars

The Astrophysical Journal
The Space Weather Around Young Suns (SWAYS) program was introduced in I. Davis et al. as a multiwavelength monitoring program for studying the activity and particle environments of nearby, young solar-type stars.
Ivey Davis, Gregg Hallinan, Nikita Kosogorov, Marin M. Anderson, John Baker, Judd D. Bowman, Rick Burruss, Ruby Byrne, Morgan Catha, Bin Chen, Xingyao Chen, Sherry Chhabra, Curt Corcoran, Larry D’Addario, Jayce Dowell, Katherine Elder, Dale Gary, Charlie Harnach, Carolyn Heffner, Greg Hellbourg, Jack Hickish, Rick Hobbs, David Hodge, Mark Hodges, Yuping Huang, Andrea Isella, Daniel C. Jacobs, Ghislain Kemby, John T. Klinefelter, Matthew Kolopanis, James Lamb, Casey Law, Nivedita Mahesh, Surajit Mondal, Brian O’Donnell, Kathryn Plant, Corey Posner, Travis Powell, Vinand Prayag, Andres Rizo, Andrew Romero-Wolf, Navtej Saini, Jun Shi, Greg Taylor, Jordan Trim, Mike Virgin, Akshatha K. Vydula, Sandy Weinreb, Scott White, David Woody, Sijie Yu, Thomas Zentmeyer, Peijin Zhang, Jeffry Zolkower   +53 more
doaj   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Observation of a Solar-like Magnetic Reconnection Event in an AGN Corona with XRISM

The Astrophysical Journal Letters
The X-ray source in active galactic nuclei (AGNs) is commonly referred to as the corona by analogy to stellar coronae. The similarities between the two suggest that the heating mechanism of AGN coronae is magnetic reconnection—as in cool stars—but this ...
Gal Vardi, Ehud Behar, Liyi Gu, Jelle Kaastra, Matteo Guainazzi, Missagh Mehdipour, Keigo Fukumura, Jon Miller, Ari Laor, Erin Kara, Megan E. Eckart, Misaki Mizumoto, Christos Panagiotou, Chen Li, Ogawa Shoji, Matilde Signorini, Keqin Zhao   +16 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

A Long-duration Superflare on the K Giant HD 251108

The Astrophysical Journal
Many giant stars are magnetically active, which causes rotational variability, chromospheric emission lines, and X-ray emission. Large outbursts in these emission features can set limits on the magnetic field strength and thus constrain the mechanism of ...
Hans Moritz Günther, Dheeraj Pasham, Alexander Binks, Stefan Czesla, Teruaki Enoto, Michael Fausnaugh, Franz-Josef Hambsch, Shun Inoue, Hiroyuki Maehara, Yuta Notsu, Jan Robrade, J. H. M. M. Schmitt, P. C. Schneider   +12 more
doaj   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

Advanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh, Peyman GhavamiNejad, Arash Khorrami Jahromi, Sanjana Srikant, Sripadh Guptha Yedire, Fatemeh Keyvani, Roozbeh Siavash Moakhar, Sajad Shiekh, Mackenzie Graham, Joe Quadrilatero, Mahla Poudineh, Sara Mahshid   +11 more
wiley   +1 more source