Results 101 to 110 of about 4,688 (310)
Stellar dynamics in the Galactic Centre: proper motions and anisotropy [PDF]
, 2000 R. Genzel +4 more
openalex +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
The Astronomical JournalWe examine the decay of perturbations in an infinite homogeneous self-gravitating model with a Maxwellian distribution function (DF) when weak collisions are present.
Evgeny V. Polyachenko, Ilia G. Shukhman
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
SMALL SCATTER AND NEARLY ISOTHERMAL MASS PROFILES TO FOUR HALF-LIGHT RADII FROM TWO-DIMENSIONAL STELLAR DYNAMICS OF EARLY-TYPE GALAXIES [PDF]
, 2015 Michele Cappellari +11 more
openalex +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Regular and Chaotic Dynamics of Triaxial Stellar Systems [PDF]
, 1998 Monica Valluri, David Merritt
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Magnetic Webs in Stellar Radiative Zones
The Astrophysical Journal LettersRotational evolution of stellar radiative zones is an old puzzle. We argue that angular momentum transport by turbulent processes induced by differential rotation is insufficient, and propose that a key role is played by “magnetic webs.” We define ...
Valentin A. Skoutnev +1 more
doaj +1 more source