Results 151 to 160 of about 171,183 (290)

S. aureus colonization and clinical symptoms remain stable upon topical XZ.700 treatment: Results of a double‐blind randomized clinical trial in patients with mild to moderate atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Aim Recovering dysbiosis may improve atopic dermatitis (AD) symptoms. XZ.700 is a recombinant chimeric endolysin that specifically targets Staphylococcus aureus and could be a new treatment option for patients with AD. The aim of this first‐in‐human study was to evaluate the safety, tolerability and efficacy of topical XZ.700 and explore the ...
Laura W. J. van der Meulen, Menthe E. Bergmans, Salma Assil, Naomi Klarenbeek, Marieke L. de Kam, Alexa J. Tibboel, Thorsten Brach, Bjorn L. Herpers, Johan Frieling, Vincent de Jong, Benthe Freyee, Martijn B. A. van Doorn, Robert Rissmann, Tessa Niemeyer–van der Kolk   +13 more
wiley   +1 more source

Molecular Hydrogen Controls the Temperatures of Flares on TRAPPIST-1

The Astrophysical Journal Letters
Early JWST observations of TRAPPIST-1 have revealed an unexpected puzzle: energetic white-light flares ( E  > 10 ^30 erg) reach temperatures of only ∼3500–4000 K, nearly 3 times cooler than typical solar flares, which peak around 9000–10,000 K.
A. I. Shapiro, N. Kostogryz, S. Seager, V. Witzke, J. de Wit, V. Vasilyev, Astrid M. Veronig, Robert Cameron, Hardi Peter, S. K. Solanki   +9 more
doaj   +1 more source

Recent studies of stellar flares across the electromagnetic spectrum

In recent years, the detection of potentially habitable planets around sun-like stars and red dwarf stars reached a new peak due to missions like Kepler/K2 and TESS.
Antoaneta Antonova
core   +1 more source

Glucocorticoid exposure and initiation of SSRIs among patients with rheumatoid arthritis: A nested case–control study in UK primary care

British Journal of Clinical Pharmacology, EarlyView.
Aim The immune system might affect the development of anxiety disorders, though mechanisms remain unclear. This nested case–control study investigates whether use of glucocorticoids, potent immunosuppressants, is associated with SSRI initiation (a proxy for pharmacologically treated mental disorders, predominantly depression and/or anxiety).
Elise J. Heesbeen, Patrick C. Souverein, Eibert R. Heerdink, Elisabeth Y. Bijlsma, Lucianne Groenink   +4 more
wiley   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Probing Starspot Dynamics on the Active M Dwarf TIC 272272592: A Multiyear TESS Study

The Astrophysical Journal
We present an analysis of temporal starspot evolution and its distribution on an active rapid rotator ( P _rot = 1.22 days), TIC 272272592, using high-precision time-series photometry from the Transiting Exoplanet Survey Satellite spanning over 3 yr. The
Rajib Kumbhakar, Soumen Mondal, Samrat Ghosh, Diya Ram, Dorothy M. Mwanzia   +4 more
doaj   +1 more source

Beyond the Reports: Cultural Pressures, Unheard Voices and the Climate Accountability Gap in Oil and Gas Sector Governance

Business Strategy and the Environment, EarlyView.
ABSTRACT Environmental governance in Nigeria's oil and gas sector remains central to global climate justice debates, yet persistent accountability failures continue to undermine meaningful environmental and social outcomes. Despite extensive regulatory frameworks, accountability in resource‐dependent contexts is frequently reduced to formal reporting ...
Hammed Afolabi, Ronita Ram, Adetola Abdulfattah Sogbesan   +2 more
wiley   +1 more source

Effect of Time-varying X-Ray Emission from Stellar Flares on the Ionization of Protoplanetary Disks

The Astrophysical Journal
X-rays have significant impacts on cold, weakly ionized protoplanetary disks by increasing the ionization rate and driving chemical reactions. Stellar flares are explosions that emit intense X-rays and are the unique source of hard X-rays with an energy ...
Haruka Washinoue, Shinsuke Takasao, Kenji Furuya   +2 more
doaj   +1 more source

The Challenges of Green Human Resource Management and Their Impact on Employees' Green Beliefs, Attitudes and Behaviours: The Case of the Nigerian Oil and Gas Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT Green human resource management is increasingly recognised as essential for integrating environmental concerns into organisational strategies. Drawing on qualitative data from 30 professionals in Nigeria's oil and gas industry, this study explores how inconsistencies between employees' environmental values and GHRM practices influence ...
Winifred Aina, Sachiko Takeda, Yumei Yang   +2 more
wiley   +1 more source

Surgical management of persistent gingival recession after sepsis‐associated gingival necrosis in a patient with systemic lupus erythematosus: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sepsis‐associated gingival necrosis is an uncommon oral manifestation that may result in extensive gingival recession after the resolution of the acute phase. Methods This report presents the 2‐year follow‐up of periodontal management in a 38‐year‐old woman with systemic lupus erythematosus, who developed septic shock accompanied by
Risako Mikami, Koji Mizutani, Ruriko Mizuno, Yuji Kabasawa, Koichiro Matsuo   +4 more
wiley   +1 more source