Results 241 to 250 of about 171,183 (290)

Perspectives on the physics of late-type stars from beyond low earth orbit, the moon and mars. [PDF]

NPJ Microgravity
Mathur S, Santos ÂRG.
europepmc   +1 more source

Mirikizumab pharmacokinetics and exposure–response in pediatric patients with moderate‐to‐severe ulcerative colitis

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 474-485, March 2025.
Abstract Mirikizumab is a p19‐directed anti‐interleukin‐23 antibody approved for the treatment of adults with moderate‐to‐severe ulcerative colitis (UC). Here, we report the first data of mirikizumab pharmacokinetics (PK) and exposure–response (E/R) relationships in pediatric participants (aged 2 to <18 years weighing >10 kg) with moderate‐to‐severe UC
Yuki Otani, Laiyi Chua, Wendy J. Komocsar, Amy Larkin, Jordan Johns, Xin Zhang   +5 more
wiley   +1 more source

The first extragalactic ultra-compact X-ray binary: A candidate black hole-white dwarf system. [PDF]

Innovation (Camb)
Ma QQ, Zhang J, Gu WM, Li Z, Weng SS, Bao T.   +5 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Lense-Thirring precession after a supermassive black hole disrupts a star. [PDF]

Nature
Pasham DR, Zajaček M, Nixon CJ, Coughlin ER, Śniegowska M, Janiuk A, Czerny B, Wevers T, Guolo M, Ajay Y, Loewenstein M.   +10 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Accreting White Dwarfs: An Unreview. [PDF]

Space Sci Rev
Scaringi S, Knigge C, de Martino D.
europepmc   +1 more source

High‐Dimensional Cumulative Sum Control Charts for Industrial Measurement Systems

Quality and Reliability Engineering International, EarlyView.
ABSTRACT High dimensional sensing in modern factories and energy assets produces thousands of correlated signals. Detecting small process shifts is challenging because many classical multivariate charts lose power or become unstable. We present two cumulative sum procedures for two sample monitoring that remain effective when the number of variables is
Osama Alhadi, Tahir Mahmood, Muhammad Riaz, Nasir Abbas   +3 more
wiley   +1 more source

Pregnancy in CTD‐interstitial lung disease: Current evidence, clinical challenges, and a proposed management algorithm

Rheumatology &Autoimmunity, EarlyView.
Summary of pregnancy management in CTD‐ILD across preconception, antenatal, and postpartum phases, emphasizing risk stratification and multidisciplinary care. 6MWT, 6‐min walk test; CTD‐ILD: connective tissue disease‐interstitial lung disease; DLCO, diffusion capacity of the lung for carbon monoxide; FVC, forced vital capacity; MDT, multidisciplinary ...
Khaled Aldhuaina, Ghaydaa Aldabie, Mohammad Abdulsalam, Ali Jawad   +3 more
wiley   +1 more source

Efficient formation of a massive quiescent galaxy at redshift 4.9. [PDF]

Nat Astron
de Graaff A, Setton DJ, Brammer G, Cutler S, Suess KA, Labbé I, Leja J, Weibel A, Maseda MV, Whitaker KE, Bezanson R, Boogaard LA, Cleri NJ, De Lucia G, Franx M, Greene JE, Hirschmann M, Matthee J, McConachie I, Naidu RP, Oesch PA, Price SH, Rix HW, Valentino F, Wang B, Williams CC.   +25 more
europepmc   +1 more source