Results 31 to 40 of about 558 (261)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Metallicity Dependence of Internal Structure Coefficients in 1–2 M⊙ Stars and Application to the Eclipsing Binary BW Aquarii

open access: yesThe Astrophysical Journal
We investigate how metallicity ( Z = 0.0001–0.03) shapes the internal structure of 1.0–2.0 M _⊙ stars by quantifying the apsidal-motion constant k _2 and the related structural coefficients η _2 and Δ _2 , together with the radial derivative d η _2 /dr ...
G. Inlek, E. Budding
doaj   +1 more source

The Impact of Recent LUNA Measurements of NeNa Reactions on 26Al Stellar Nucleosynthesis

open access: yesUniverse
Recent measurements performed by the LUNA(Laboratory for Underground Nuclear Astrophysics) collaboration between 2019 and 2024 have provided the most precise direct determinations to date of several key reaction rates in the NeNa cycle, specifically the ...
Umberto Battino   +8 more
doaj   +1 more source

Rotation and stellar evolution

open access: yesEPJ Web of Conferences, 2013
The effects of rotation on the evolution and properties of low-mass stars are first discussed from the pre-main sequence to the red giant phase. We then briefly indicate how some observational constraints available for these stars can help us progress in
Eggenberger P.
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An Expanded Set of Los Alamos OPLIB Tables in MESA: Type-1 Rosseland-mean Opacities and Solar Models

open access: yesThe Astrophysical Journal
We present a set of 1194 Type-1 Rosseland-mean opacity tables for four different metallicity mixtures. These new Los Alamos OPLIB atomic radiative opacity tables are an order of magnitude larger in number than any previous opacity table release, and span
Ebraheem Farag   +13 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

High-order Gravity-mode Period Spacing Patterns of Intermediate-mass (1.5 M⊙ < M < 3 M⊙) Main-sequence Stars. I. Perturbative Analysis

open access: yesThe Astrophysical Journal
Theoretical study of the high-order gravity-mode period spacing (Δ P _g ) pattern is relevant to a better understanding of the internal properties of intermediate-mass (1.5 M _⊙  
Yoshiki Hatta, Takashi Sekii
doaj   +1 more source

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