Results 31 to 40 of about 182,216 (290)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

On the Possibility of Chemically Driven Convection in Red Giants: Implications for the He-core Flash and Mixing above the Red Giant Branch Bump

The Astrophysical Journal
Turbulent mixing remains one of the primary uncertainties in the modeling of stellar interiors. In stellar evolution simulations, regions where mixing occurs are typically identified using instability criteria. A particularly interesting situation arises
M. Miguel Ocampo, Marcelo M. Miller Bertolami   +1 more
doaj   +1 more source

Recent advances in modeling stellar interiors [PDF]

Astrophysics and Space Science, 2010
Advances in stellar interior modeling are being driven by new data from large-scale surveys and high-precision photometric and spectroscopic observations. Here we focus on single stars in normal evolutionary phases; we will not discuss the many advances in modeling star formation, interacting binaries, supernovae, or neutron stars. We review briefly: 1)
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Physical mechanisms of mixing in stellar interiors [PDF]

Symposium - International Astronomical Union, 1984
The different mechanisms by which mixing can take place in stellar interiors are considered : the classical Rayleigh-Benard instability with penetrative convection and over-shooting, semi-convection, gravitationnal and radiative settling, turbulent mixing.
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Stellar magnetism : empirical trends with age and rotation [PDF]

, 2014
AAV acknowledges support from a Royal Astronomical Society Fellowship and from the Swiss National Science Foundation via an Ambizione Fellowship. SGG acknowledges support from the Science and Technology Facilities Council (STFC) via an Ernest Rutherford ...
G. Hussain, Jeffers, S., Do Nascimento Jr., J.D., Waite, I.A., R. Fares, Folsom, C. P., Gregory, S. G.; id_orcid, P. Petit, Gregory, S. G., Hussain, G., do Nascimento, J. D., Donati, J. -F., Jardine, M., M. Jardine, Vidotto, A. A., Petit, P., I. A. Waite, Marsden, S., S. Marsden, Vidotto, A. A, Nascimento Júnior, José Dias do, Donati, J.F., J. Bouvier, J. Morin, J. D. Do Nascimento, Nascimento, J. D. Do, C. P. Folsom, Donati, J. F., Morin, J., Bouvier, J., J. F. Donati, Waite, I. A., Gregory, S.G., Jeffers, Sandra V., Fares, R., Hussain, G. A. J., Cameron, A. C., A. A. Vidotto, Morin, Julien, do Nascimento Jr., J.-D., A. C. Cameron, S. Jeffers, Cameron, A.C., S. G. Gregory, Vidotto, A.A., Folsom, C.P.   +45 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The Physics of Stellar Interiors

, 2022
These are the slides for a seminar talk that I gave on August 9, 2022 as part of the Space Science and Security Summer Seminar Series at Lawrence Livermore National Laboratory.  The talk gives an overview of some aspects of stellar hydrodynamics, and describes how realistic hydrodynamic simulations are used to improve stellar structure and evolution ...
openaire   +1 more source

Primordial Lithium from Globular Cluster Turnoff Stars: M13 and M71

The Astrophysical Journal
During Big Bang nucleosynthesis (BBN) in the first 15 minutes of the Universe, some ^7 Li was created along with isotopes of H and He. The determination of that primordial value of Li can help constrain the conditions at that time.
Ann Merchant Boesgaard, Constantine P. Deliyannis   +1 more
doaj   +1 more source