Results 71 to 80 of about 17,877 (291)

The Interiors of Giant Planets: Models and Outstanding Questions

open access: yes, 2005
We know that giant planets played a crucial role in the making of our Solar System. The discovery of giant planets orbiting other stars is a formidable opportunity to learn more about these objects, what is their composition, how various processes ...
Bolton SJ   +11 more
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Impact of Newly Measured Nuclear Reaction Rates on 26Al Ejected Yields from Massive Stars

open access: yesUniverse
Over the last three years, the rates of all the main nuclear reactions involving the destruction and production of 26Al in stars (26Al(n, p)26Mg, 26Al(n, α)23Na, 26Al(p, γ)27Si and 25Mg(p, γ)26Al) have been re-evaluated thanks to new high-precision ...
Umberto Battino   +4 more
doaj   +1 more source

Asteroseismology and spectropolarimetry: opening new windows on the internal dynamics of massive stars

open access: yes, 2014
In this article, we show how asteroseismology and spectropolarimetry allow to probe dynamical processes in massive star interiors. First, we give a summary of the state-of-the-art.
Mathis, Stéphane, Neiner, Coralie
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

A Core-sensitive Mixed f/g-mode of the Sun Predicted by Wave Topology and Hydrodynamical Simulation

open access: yesThe Astrophysical Journal Letters
Helioseismology has revolutionized our understanding of the Sun by analyzing its global oscillation modes. However, the solar core remains elusive, limiting a full understanding of its evolution.
Arthur Le Saux   +4 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Fast and Slow Crystallization-driven Convection in White Dwarfs

open access: yesThe Astrophysical Journal
We investigate crystallization-driven convection in carbon–oxygen white dwarfs. We present a version of the mixing length theory that self-consistently includes the effects of thermal diffusion and composition gradients, and provides solutions for the ...
Matias Castro-Tapia   +2 more
doaj   +1 more source

Using magnetic fluids to simulate convection in a central force field in the laboratory [PDF]

open access: yesNonlinear Processes in Geophysics, 2005
Large-scale convection in planetary or stellar interiors plays a significant role but it is difficult to reproduce the central force field of those systems in experimental studies.
W.-G. Früh
doaj  

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