Results 131 to 140 of about 143,610 (241)

The stellar initial mass function [PDF]

open access: yesProceedings of the International Astronomical Union, 2006
Abstract The IMF UNIVERSALITY HYPOTHESIS cannot be discarded despite the existence of the CLUSTER IMF THEOREM. This means that the currently existing star-formation theory fails to describe the stellar outcome. The IGIMF THEOREM, however, predicts a variation of galaxy-wide IMFs in dependence of the galaxy's star-formation rate even if the IMF ...
openaire   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

The Outskirt Stellar Mass of Low-redshift Massive Galaxies Is an Excellent Halo Mass Proxy in Illustris/IllustrisTNG Simulations

open access: yesThe Astrophysical Journal
Recent observations suggest that the extended stellar halos of low-redshift massive galaxies are tightly connected to the assembly of their dark matter halos.
Shuo Xu   +6 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Dynamical Mass of the Ophiuchus Intermediate-mass Stellar System S1 with DYNAMO-VLBA

open access: yesThe Astronomical Journal
We report dynamical mass measurements of the individual stars in the most luminous and massive stellar member of the nearby Ophiuchus star-forming region, the young tight binary system S1.
Jazmín Ordóñez-Toro   +10 more
doaj   +1 more source

The Progenitors and Lifetimes of Planetary Nebula

open access: yes, 2015
Planetary Nebulae (PNe) are amongst the most spectacular objects produced by stellar evolution, but the exact identity of their progenitors has never been established for a large and homogeneous observational sample.
Badenes, Carles   +2 more
core   +1 more source

Stellar-Mass Black Holes

open access: yesSymmetry
Stellar-mass black holes (3 M⊙≲MBH≲150 M⊙) are the natural product of the evolution of heavy stars (Mstar≳20 M⊙). In our Galaxy, we expect that 108–109 stellar-mass black holes have been formed from the gravitational collapse of heavy stars, but currently we know fewer than 100 objects.
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy

open access: yesMolecular Oncology, EarlyView.
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti   +3 more
wiley   +1 more source

Discovery and Characterization of Two Ultrafaint Dwarfs outside the Halo of the Milky Way: Leo M and Leo K

open access: yesThe Astrophysical Journal
We report the discovery of two ultrafaint dwarf galaxies, Leo M and Leo K, that lie outside the halo of the Milky Way (MW). Using Hubble Space Telescope imaging of the resolved stars, we create color–magnitude diagrams reaching the oldest main-sequence ...
Kristen. B. W. McQuinn   +6 more
doaj   +1 more source

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