Results 141 to 150 of about 143,610 (241)

The stellar disk thickness of LSB galaxies

open access: yes, 2004
We present surface photometry results for a sample of eleven edge-on galaxies observed with the 6m telescope at the Special Astrophysical Observatory (Russia).
Barteldrees A.   +15 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The Heavy Metal Survey: Star Formation Constraints and Dynamical Masses of 21 Massive Quiescent Galaxies at z = 1.3–2.3

open access: yesThe Astrophysical Journal
In this paper, we present the Heavy Metal Survey, which obtained ultradeep medium-resolution spectra of 21 massive quiescent galaxies at 1.3 < z < 2.3 with Keck/LRIS and MOSFIRE.
Mariska Kriek   +16 more
doaj   +1 more source

Breaking down the link between luminous and dark matter in massive galaxies

open access: yes, 2011
We present a study on the clustering of a stellar mass selected sample of galaxies with stellar masses M*>10^10Msol at redshifts 0 ...
Christopher J. Conselice   +4 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

JADES + JEMS: A Detailed Look at the Buildup of Central Stellar Cores and Suppression of Star Formation in Galaxies at Redshifts 3 < z < 4.5

open access: yesThe Astrophysical Journal
We present a spatially resolved study of stellar populations in six galaxies with stellar masses M _* ∼ 10 ^10 M _☉ at z ∼ 3.7 using 14-filter James Webb Space Telescope (JWST)/NIRCam imaging from the JADES and JEMS surveys. The six galaxies are visually
Zhiyuan Ji   +32 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

LAMOST Reveals Long-lived Protoplanetary Disks

open access: yesThe Astronomical Journal
While both observations and theories demonstrate that protoplanetary disks are not expected to live much longer than ∼10 Myr, several examples of prolonged disks have been observed in the past.
Xiao-Long Wang   +4 more
doaj   +1 more source

Universal IMF vs dark halo response in early-type galaxies: breaking the degeneracy with the fundamental plane

open access: yes, 2013
We use the relations between aperture stellar velocity dispersion (\sigma_ap), stellar mass (M_sps), and galaxy size (R_e) for a sample of \sim 150,000 early-type galaxies from SDSS/DR7 to place constraints on the stellar initial mass function (IMF) and ...
Aaron A. Dutton   +98 more
core   +1 more source

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