Results 131 to 140 of about 18,267 (299)

Upper Limits on Stellar Companions to the Kepler-34 and Kepler-35 Systems

The Astronomical Journal
We obtained new spectra of Kepler-34 and Kepler-35 with Keck-HIRES—nearly a decade after these systems were originally characterized with this spectrograph and other instruments—to search for radial velocity (RV) trends from a potential third stellar ...
Carlos Jurado, Lauren M. Weiss, Laura Daclison, Benjamin M. Tofflemire, Jerome A. Orosz, William F. Welsh   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

THE SLOAN LENS ACS SURVEY. IX. COLORS, LENSING, AND STELLAR MASSES OF EARLY-TYPE GALAXIES

, 2009
We present the current photometric data set for the Sloan Lens ACS (SLACS) Survey, including Hubble Space Telescope (HST) photometry from Advanced Camera for Surveys, WFPC2, and NICMOS.
Auger, MW, Bolton, AS, Moustakas, LA, Treu, T, Marshall, PJ, Gavazzi, R, Auger, M. W., Bundy, K, Bolton, A. S., Gavazzi, R., Marshall, P. J., Koopmans, LVE, Bundy, K., Treu, T., Koopmans, L. V. E., Moustakas, L. A., Marshall, Philip   +16 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Photometric stellar masses for galaxies in DESI Legacy Imaging Surveys

In many areas of extragalactic astrophysics, we need to convert the luminosity of a galaxy into its stellar mass. In this work, we aim to find a simple and effective formula to estimate the stellar mass from the images of galaxies delivered by the ...
Jiří Eliášek, Ivana Ebrová, Michal Bílek   +2 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The stellar masses of ∼ 40 000 UV selected Galaxies from the WiggleZ survey at 0.3z1.0: analogues of Lyman break galaxies?

, 2013
We characterize the stellar masses and star formation rates in a sample of ∼40 000 spectroscopically confirmed UV-luminous galaxies at 0.3 5σ in the UKIDSS-LAS at all redshifts.
S. Croom (18997346), K. Forster (7720310), G. B. Poole (18997856), M. Colless (7696259), M. Gladders (7616048), T. K. Wyder (18998975), E. Wisnioski (18997886), S. Brough (16219913), D. Gilbank (18998954), B. Jelliffe (18998957), M. Banerji (7662782), Chris Blake (18927049), I.-h. Li (18998963), Darren Croton (18926746), M. J. Drinkwater (18997325), Karl Glazebrook (18926938), R. J. Jurek (18998960), R. Sharp (7613981), T. M. Davis (18998951), M. Pracy (18998969), H. K. C. Yee (18998978), K. Pimbblet (18997553), B. Madore (18997370), D. C. Martin (18998966), Warrick Couch (18925639), D. Woods (18998972), C. Contreras (6157979)   +26 more
core   +1 more source

The Lower Limit of Dynamical Black Hole Masses Detectable in Virgo Compact Stellar Systems Using the JWST/NIRSpec IFU

The Astrophysical Journal
Due to observational challenges, the mass function of black holes (BH) at lower masses is poorly constrained in the local universe. Understanding the occupation fraction of BHs in low-mass galaxies is crucial for constraining the origins of supermassive ...
Behzad Tahmasebzadeh, Andrew Lapeer, Eugene Vasiliev, Monica Valluri, Matthew A. Taylor, Solveig Thompson   +5 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

On the stellar masses of IRAC detected Lyman Break Galaxies at z similar to 3

, 2010
We present results of a large survey of the mid-infrared (mid-IR) properties of 248 Lyman Break Galaxies (LBGs) with confirmed spectroscopic redshift using deep Spitzer/Infrared Array Camera (IRAC) observations in six cosmological fields.
Fazio GG, Huang, J-S, Rigopoulou, Dimitra, Huang J-, Fazio, GG, Magdis GE, Rigopoulou D, Magdis, GE, Rigopoulou, D   +8 more
core   +1 more source