Results 161 to 170 of about 18,267 (299)

Luminosity and Stellar Mass Functions of Faint Photometric Satellites around Spectroscopic Central Galaxies from DESI Year-1 Bright Galaxy Survey

The Astrophysical Journal
We measure the luminosity functions (LFs) and stellar mass functions (SMFs) of photometric satellite galaxies around spectroscopically identified isolated central galaxies (ICGs). The photometric satellites are from the DESI Legacy Imaging Surveys (DR9),
Wenting Wang, Xiaohu Yang, Yipeng Jing, Ashley J. Ross, Malgorzata Siudek, John Moustakas, Samuel G. Moore, Shaun Cole, Carlos Frenk, Jiaxi Yu, Sergey E. Koposov, Jiaxin Han, Zhenlin Tan, Kun Xu, Yizhou Gu, Yirong Wang, Oleg Y. Gnedin, Jessica Nicole Aguilar, Steven Ahlen, Davide Bianchi, David Brooks, Todd Claybaugh, Axel de la Macorra, Arjun Dey, Peter Doel, Jaime E. Forero-Romero, Enrique Gaztañaga, Satya Gontcho A Gontcho, Gaston Gutierrez, Klaus Honscheid, Mustapha Ishak, Theodore Kisner, Martin Landriau, Laurent Le Guillou, Marc Manera, Aaron Meisner, Ramon Miquel, Seshadri Nadathur, Claire Poppett, Francisco Prada, Ignasi Pérez-Ràfols, Graziano Rossi, Eusebio Sanchez, David Schlegel, Hee-Jong Seo, Joseph Harry Silber, David Sprayberry, Gregory Tarlé, Benjamin Alan Weaver, Hu Zou   +49 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

LAMOST Reveals Long-lived Protoplanetary Disks

The Astronomical Journal
While both observations and theories demonstrate that protoplanetary disks are not expected to live much longer than ∼10 Myr, several examples of prolonged disks have been observed in the past.
Xiao-Long Wang, Min Fang, Yao Liu, Miao-Miao Zhang, Wen-Yuan Cui   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The Shape of FIREbox Galaxies and a Potential Tension with Low-mass Disks

The Astrophysical Journal
We study the intrinsic and observable shapes of approximately 700 star-forming galaxies with stellar masses of 10 ^8 –10 ^11 M _⊙ from the FIREbox simulation at z = 0.
Courtney Klein, Jenny D. Wang, Luke Y. Xia, James S. Bullock, Jorge Moreno, Robert Feldmann, Francisco J. Mercado, Claude-André Faucher-Giguère, Jonathan Stern, N. Nicole Sanchez, Abdelaziz Hussein, Michelle S. Park   +11 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Software for Predicting Stellar Masses of the First Galaxies using Graph Neural Networks

<p>Dataset and code notebooks for "Predicting Stellar Masses of the First Galaxies using Graph Neural Networks" (Horvath et al.
Horvath, Vincent A., Wise, John H., Sethuram, Snigdaa S.   +2 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source