Results 161 to 170 of about 143,610 (241)

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Mass of Cepheid V350 Sgr Incorporating Interferometry and the Companion Mass

The Astrophysical Journal
The system V350 Sgr has a classical Cepheid for the primary. Interferometry is presented for the system, and the full orbit is determined. The mass of the companion has been determined from an International Ultraviolet Explorer spectrum and comparison ...
Nancy Remage Evans, Alexandre Gallenne, Pierre Kervella, H. Moritz Günther, Joanna Kuraszkiewicz, Richard I. Anderson, Charles Proffitt, Antoine Mérand, Boris Trahin, Giordano Viviani, Shreeya Shetye   +10 more
doaj   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

The Orbit and Dynamical Mass of Polaris: Observations with the CHARA Array

The Astrophysical Journal
The 30 yr orbit of the Cepheid Polaris has been followed with observations by the Center for High Angular Resolution Astronomy (CHARA) Array from 2016 through 2021.
Nancy Remage Evans, Gail H. Schaefer, Alexandre Gallenne, Guillermo Torres, Elliott P. Horch, Richard I. Anderson, John D. Monnier, Rachael M. Roettenbacher, Fabien Baron, Narsireddy Anugu, James W. Davidson Jr., Pierre Kervella, Garance Bras, Charles Proffitt, Antoine Mérand, Margarita Karovska, Jeremy Jones, Cyprien Lanthermann, Stefan Kraus, Isabelle Codron, Howard E. Bond, Giordano Viviani   +21 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

How Invisible Stellar Halos Bias Our Understanding of Ultrafaint Galaxies

The Astrophysical Journal
We explore how a realistic surface brightness (SB) detection limit of μ _V ≈ 32.5 mag arcsec ^−2 for stars at the edges of ultrafaint galaxies affects our ability to infer their underlying properties.
Coral Wheeler, Jorge Moreno, M. Katy Rodriguez Wimberly, Francisco J. Mercado, James S. Bullock, Michael Boylan-Kolchin, Pratik J. Gandhi, Sarah R. Loebman, Philip F. Hopkins   +8 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Exposing Line Emission: The Systematic Differences of Measuring Galaxy Stellar Masses with JWST NIRCam Medium versus Wide Band Photometry

The Astrophysical Journal Letters
Photometrically derived stellar masses are known to suffer from systematic uncertainties, particularly due to nebular emission contributions to the spectral energy distribution (SED).
Ghassan T. E. Sarrouh, Adam Muzzin, Kartheik G. Iyer, Lamiya Mowla, Sunna Withers, Nicholas S. Martis, Roberto Abraham, Yoshihisa Asada, Maruša Bradač, Gabriel B. Brammer, Guillaume Desprez, Vince Estrada-Carpenter, Jasleen Matharu, Gaël Noirot, Marcin Sawicki, Victoria Strait, Chris J. Willott, Johannes Zabl   +17 more
doaj   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Insights into Planet Formation from the Ages, Masses, and Elemental Abundances of Host Stars

The Astrophysical Journal
How planetary systems form and evolve is a key question in astronomy. Revealing how host star properties—such as elemental abundances, age, and mass—differ from those of nonhost stars, and how they correlate with planetary characteristics such as radius,
Xunzhou Chen, Tiancheng Sun, Lifei Ye
doaj   +1 more source