Results 71 to 80 of about 197,228 (295)
Reverse Shock Revisited in Cassiopeia A with Chandra
The Astrophysical JournalUsing data from the Chandra X-ray Observatory, we revisit the reverse shock in the supernova remnant (SNR) Cassiopeia A. Based on spectroscopy of a series of annuli in the northwest (NW) and southeast (SE), we get the radial profiles of the S/Si K α line
Yin Wu, X. J. Yang
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Introduction to nuclear astrophysics
, 2009 In the first lecture of this volume, we will present the basic fundamental ideas regarding nuclear processes occurring in stars. We start from stellar observations, will then elaborate on some important quantum-mechanical phenomena governing nuclear ...
Iliadis, Christian
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Astrophysical JournalBlue large-amplitude pulsators (BLAPs) are a recently discovered group of hot pulsating stars whose evolutionary status remains uncertain. Their proposed progenitors are either ≃0.3 M _⊙ shell H-burning stars or ≃1.0 M _⊙ core He-burning stars, both ...
Susmita Das +2 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
MESA Isochrones and Stellar Tracks (MIST). III. The White Dwarf Cooling Sequence
The Astrophysical Journal Supplement SeriesWe present a substantial update to the MESA Isochrones and Stellar Tracks (MIST) library, extending the MIST model grids and isochrones down the white dwarf (WD) cooling sequence with realistic physics for WD cooling timescales.
Evan B. Bauer +5 more
doaj +1 more source
Stellarator physics evaluation studies
, 1983 Stellarator/torsatron configurations with a wide range of parameters have been evaluated and compared in terms of their vacuum field topology, magnetohydrodynamic equilibrium and stability, and guiding center orbit confinement. The torsatron configurations are found to be the most suitable choice for a near-term physics experiment.
B. A. Carreras, J. H. Harris, J. A. Rome
openaire +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Flexible Stellarator Physics Facility
We propose to build a Flexible Stellarator Physics Facility to explore promising regions of the vast parameter space of disruption-free stellarator solutions for Fusion Pilot Plants (FPPs).
Parra, F. I. +23 more
openaire +3 more sources