Results 71 to 80 of about 197,159 (337)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Reverse Shock Revisited in Cassiopeia A with Chandra

The Astrophysical Journal
Using data from the Chandra X-ray Observatory, we revisit the reverse shock in the supernova remnant (SNR) Cassiopeia A. Based on spectroscopy of a series of annuli in the northwest (NW) and southeast (SE), we get the radial profiles of the S/Si K α line
Yin Wu, X. J. Yang
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Probing the non-thermal physics of stellar bow shocks using radio observations [PDF]

, 2023
J. R. Martinez, S. del Palacio, V. Bosch-Ramón   +2 more
openalex   +1 more source

The s Process: Nuclear Physics, Stellar Models, Observations

, 2010
Nucleosynthesis in the s process takes place in the He burning layers of low mass AGB stars and during the He and C burning phases of massive stars. The s process contributes about half of the element abundances between Cu and Bi in solar system material.
Allen, B., Aoki, W., Aoki, W., Beer, H., Beer, H., Bisterzo, S., Bisterzo, S., Borella, A., Bradley, T., Chau, L., Christlieb, N., Clayton, D., Cristallo, S., de L. Musgrove, A., Diehl, R., Dillmann, I., Dillmann, I., Dupraz, C., Edvardsson, B., F. Käppeler, F. Rau, Freytag, B., Fürst, E., Gallino, R., Goriely, S., Gratton, R., Guber, K., Herwig, F., Herwig, F., Hill, V., Jehin, E., Koning, A., Käppeler, F., Lambert, D., Langer, N., Lisowski, P., Macklin, R., Macklin, R., Macklin, R., Macklin, R., Meusel, O., Perey, F., Prantzos, N., Péquignot, D., R. Gallino, Ratzinger, U., Rau, F., S. Bisterzo, Sadakane, K., Spencer, R., Straniero, O., Suda, T., Tain, J., Thielemann, F.-K., Van Winckel, H., Wako Aoki, Ward, R., Weigert, A., Wisshak, K., Woodward, P.   +59 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Boron Abundances in Early B Dwarfs of the Galactic Open Cluster NGC 3293

The Astrophysical Journal
New boron abundances or upper limits have been determined for eight early B stars in the young Galactic open cluster NGC 3293, using UV spectra obtained by the Hubble Space Telescope Cosmic Origins Spectrograph.
Charles R. Proffitt, Harim Jin, Simone Daflon, Daniel J. Lennon, Norbert Langer, Katia Cunha, Talawanda Monroe   +6 more
doaj   +1 more source

Introduction to nuclear astrophysics

, 2009
In the first lecture of this volume, we will present the basic fundamental ideas regarding nuclear processes occurring in stars. We start from stellar observations, will then elaborate on some important quantum-mechanical phenomena governing nuclear ...
Iliadis, Christian
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source