Results 91 to 100 of about 197,789 (295)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Oxidation–Deuteration Processes of Large, Astronomically Relevant Cationic Polycyclic Aromatic Hydrocarbons

The Astrophysical Journal
In interstellar environments, gas-phase polycyclic aromatic hydrocarbon (PAH) predominantly involves (photo)fragmentation, hydrogenation, and oxidation chemical routes, which lead to the formation of complex organic species.
Xiaoyi Hu, Nian Zhao, Congcong Zhang, Xuejuan Yang, Alexander G. G. M. Tielens, Junfeng Zhen   +5 more
doaj   +1 more source

Can stellar activity make a planet seem misaligned?

, 2016
Several studies have shown that the occultation of stellar active regions by the transiting planet can generate anomalies in the high-precision transit light curves, and these anomalies may lead to an inaccurate estimate of the planetary parameters (e.g.,
Dreizler, S., Figueira, P., Oshagh, M., Reiners, A., Santos, N. C.   +4 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

An Expanded Set of Los Alamos OPLIB Tables in MESA: Type-1 Rosseland-mean Opacities and Solar Models

The Astrophysical Journal
We present a set of 1194 Type-1 Rosseland-mean opacity tables for four different metallicity mixtures. These new Los Alamos OPLIB atomic radiative opacity tables are an order of magnitude larger in number than any previous opacity table release, and span
Ebraheem Farag, Christopher J. Fontes, F. X. Timmes, Earl P. Bellinger, Joyce A. Guzik, Evan B. Bauer, Suzannah R. Wood, Katie Mussack, Peter Hakel, James Colgan, David P. Kilcrease, Manolo E. Sherrill, Tryston C. Raecke, Morgan T. Chidester   +13 more
doaj   +1 more source

Modules for Experiments in Stellar Astrophysics (MESA)

, 2010
Stellar physics and evolution calculations enable a broad range of research in astrophysics. Modules for Experiments in Stellar Astrophysics (MESA) is a suite of open source libraries for a wide range of applications in computational stellar astrophysics.
Aaron Dotter, Allard, Arnett, Asplund, Bahcall, Baraffe, Bildsten, Bill Paxton, Bjork, Blöcker, Burrows, Böhm-Vitense, Calder, Calder, Cameron, Cassisi, Castelli, Chabrier, Chabrier, Chandrasekhar, Clayton, Cox, Cumming, Cyburt, de Jager, Dotter, Dotter, Dziembowski, Eddington, Eggleton, Falk Herwig, Ferguson, Frank Timmes, Fujimoto, Grevesse, Hairer, Hansen, Hauschildt, Hauschildt, Heger, Heger, Herwig, Herwig, Herwig, Hofmeister, Kippenhahn, Kippenhahn, Kippenhahn, Kunz, Lars Bildsten, Limongi, Limongi, Lodders, Lugaro, Madhusudhan, Nieuwenhuijzen, Nugis, Oberkampf, Pierre Lesaffre, Pietrinferni, Pols, Press, Rauscher, Reimers, Roache, Rogers, Sakharuk, Schwarzschild, Serenelli, Shen, Soderlind, Starrfield, Steffen, Thomas, Timmes, Timmes, VandenBerg, Weinberg, Weiss, Woosley, Yakovlev, Young, Zingale   +82 more
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Pulsation models of O-rich and C-rich long period variables

EPJ Web of Conferences, 2017
The intrinsic variability of luminous red giants is an observable providing important information about stellar structure and evolution. Our aim is to provide a solid theoretical background to the wide amount of data coming from present and future ...
Trabucchi Michele, Marigo Paola, Montalbán Josefina, Wood Peter R., Girardi Léo   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Physics of Stellar Coronae

, 2009
Stellar coronae, defined by the ensemble of magnetic field structures above stellar photospheres and chromospheres together with their thermal or non-thermal plasma content, play an important role in our understanding of stellar magnetic fields, the stellar magnetic dynamo, and interactions between a star and its environment.
openaire   +2 more sources