Results 91 to 100 of about 14,785 (302)

The Oxidation–Deuteration Processes of Large, Astronomically Relevant Cationic Polycyclic Aromatic Hydrocarbons

open access: yesThe Astrophysical Journal
In interstellar environments, gas-phase polycyclic aromatic hydrocarbon (PAH) predominantly involves (photo)fragmentation, hydrogenation, and oxidation chemical routes, which lead to the formation of complex organic species.
Xiaoyi Hu   +5 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Black Hole Mergers and Their Electromagnetic Counterparts [PDF]

open access: yes, 2011
Over the past ten years it has become increasingly clear that most, if not all, galaxies have super-massive black holes lurking in their cores. The implications for this are large as they not only have significant effects on the host galaxies, far beyond
Bode, Jason Nathaniel
core   +1 more source

An Expanded Set of Los Alamos OPLIB Tables in MESA: Type-1 Rosseland-mean Opacities and Solar Models

open access: yesThe Astrophysical Journal
We present a set of 1194 Type-1 Rosseland-mean opacity tables for four different metallicity mixtures. These new Los Alamos OPLIB atomic radiative opacity tables are an order of magnitude larger in number than any previous opacity table release, and span
Ebraheem Farag   +13 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A study of U Aquarii and the nucleosynthesis of neutrons and S-process elements in evolved stars of low mass

open access: yes, 2014
The origin of the extreme hydrogen deficiency observed in the R Coronae Borealis (RCrB) stars remains poorly understood. A likely mechanism for producing this deficiency is one whereby the original hydrogen envelope of the star is engulfed and ...
Malaney, Robert A.
core  

Neutrino treatment in multidimensional astrophysical simulations : a new spectral scheme [PDF]

open access: yes, 2014
Neutrinos play a central role in modern physics and astrophysics. Their extremely weak interaction rate with baryons and other leptons makes their detection on the Earth difficult and challenging.
Perego, Albino
core   +1 more source

Pulsation models of O-rich and C-rich long period variables

open access: yesEPJ Web of Conferences, 2017
The intrinsic variability of luminous red giants is an observable providing important information about stellar structure and evolution. Our aim is to provide a solid theoretical background to the wide amount of data coming from present and future ...
Trabucchi Michele   +4 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Simulations of X-ray bursts and superbursts [PDF]

open access: yes, 2015
Observations of neutron star in binary systems provide powerful constrains on the physics at the surface of neutron stars. During the accretion of matter from the companion star, periodic nuclear explosion are triggered in the outer layers of the neutron
Fehlmann, Sofie
core   +1 more source

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