Results 51 to 60 of about 1,795 (299)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Multi-periodic photospheric pulsations and connected wind structures in HD64760

open access: yes, 2006
We report on the results of an extended optical spectroscopic monitoring campaign on the early-type B supergiant HD 64760 (B0.5 Ib) designed to probe the deep-seated origin of spatial wind structure in massive stars.
A. Kaufer   +7 more
core   +1 more source

Asteroseismology of massive stars: new insights of stellar interiors from their pulsations

open access: yes, 2021
Massive stars are important metal factories which provide energy and chemical feedback to their surroundings. However, stellar evolution models currently contain large theoretical uncertainties for physical mechanisms at work in the deep interiors of ...
Bowman, D.M.
core   +1 more source

Asteroseismic Characterization of 142 Solar-like Oscillators Hosting Confirmed Exoplanets

open access: yesThe Astrophysical Journal Supplement Series
We present the largest catalog of exoplanet host stars with solar-like oscillations compiled to date, providing a powerful resource for refining stellar and planetary characterization via asteroseismology.
Wen-Xu Lin   +8 more
doaj   +1 more source

Bifurcation in Hydrodynamic Models of Stellar Pulsation [PDF]

open access: yesInternational Astronomical Union Colloquium, 1993
AbstractPhenomena of bifurcation in hydrodynamic stellar models of radial pulsation are reviewed. By changing control parameters of models, we can see qualitatively different pulsation behaviors in hydrodynamic models with transitions due to various types of bifurcation.In weakly dissipative models (classical Cepheids).
openaire   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Variability of Known Exoplanet Host Stars Observed by TESS

open access: yesThe Astronomical Journal, 2023
Both direct and indirect methods of exoplanet detection rely upon detailed knowledge of the potential host stars. Such stellar characterization allows for accurate extraction of planetary properties, as well as contributing to our overall understanding ...
Emilie R. Simpson   +5 more
doaj   +1 more source

The potential of Shannon entropy to find the large separation of δ Scuti stars: The entropy spectrum

open access: yesFrontiers in Astronomy and Space Sciences, 2022
This study explores the use of Shannon entropy to find periodic patterns in the oscillation spectra of δ Scuti stars. We have developed a new diagnostic tool for detecting potential patterns that scans for minimal entropic states in the well-known ...
J. C. Suárez
doaj   +1 more source

Challanges for stellar pulsation and evolution theory [PDF]

open access: yesCommunications in Asteroseismology, 2009
During the last few decades, great effort has been made towards understanding hydrodynamical processes which determine the structure and evolution of stars. Up to now, the most stringent constraints have been provided by helioseismology and stellar cluster studies. However, the contribution of asteroseismology becomes more and more important, giving us
openaire   +2 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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