Results 71 to 80 of about 1,795 (299)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

APOKASC-3: The Third Joint Spectroscopic and Asteroseismic Catalog for Evolved Stars in the Kepler Fields

The Astrophysical Journal Supplement Series
In the third APOKASC catalog, we present data for the complete sample of 15,808 evolved stars with APOGEE spectroscopic parameters and Kepler asteroseismology.
Marc H. Pinsonneault, Joel C. Zinn, Jamie Tayar, Aldo Serenelli, Rafael A. García, Savita Mathur, Mathieu Vrard, Yvonne P. Elsworth, Benoit Mosser, Dennis Stello, Keaton J. Bell, Lisa Bugnet, Enrico Corsaro, Patrick Gaulme, Saskia Hekker, Marc Hon, Daniel Huber, Thomas Kallinger, Kaili Cao, Jennifer A. Johnson, Bastien Liagre, Rachel A. Patton, Ângela R. G. Santos, Sarbani Basu, Paul G. Beck, Timothy C. Beers, William J. Chaplin, Katia Cunha, Peter M. Frinchaboy, Léo Girardi, Diego Godoy-Rivera, Jon A. Holtzman, Henrik Jönsson, Szabolcs Mészáros, Claudia Reyes, Hans-Walter Rix, Matthew Shetrone, Verne V. Smith, Taylor Spoo, Keivan G. Stassun, Ji Wang   +40 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Energetic properties of stellar pulsations across the Hertzsprung-Russell diagram

EPJ Web of Conferences, 2015
I will review types of modes which are observed in stars with different masses and on various evolutionary stages. In particular, I will focus on energetic aspects of oscillation modes, i.e., excitation, distribution of kinetic energy, mode amplitude and
Daszyńska-Daszkiewicz Jadwiga
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Modules for Experiments in Stellar Astrophysics (MESA): Binaries, Pulsations, and Explosions

, 2019
<p>MESA inlists associated with <a href="https://ui.adsabs.harvard.edu/?#abs/2015ApJS..220...15P">Modules for Experiments in Stellar Astrophysics (MESA): Binaries, Pulsations, and Explosions</a></p ...
Bildsten, Lars, Townsley, Dean M. (6474017), Cantiello, Matteo, Langer, N. (6474011), Dessart, Luc, Farmer, R (6446699), Timmes, F. X., Timmes, F. X. (6451724), Hu, H. (6474008), Bauer, Evan B., Langer, N., Bauer, Evan B. (6442946), Marchant, Pablo, Schwab, Josiah, Schwab, Josiah (6446312), Townsend, R. H. D., Paxton, Bill, Hu, H., Townsend, R. H. D. (6474014), Farmer, R, Cantiello, Matteo (6467747), Marchant, Pablo (6473126), Bildsten, Lars (6446330), Townsley, Dean M., Paxton, Bill (6451766), Dessart, Luc (6446708)   +25 more
core   +1 more source

It’s Not Just a Phase: Oblique Pulsations in Magnetic Red Giants and Other Stochastic Oscillators

The Astrophysical Journal Letters
Magnetic fields play a significant role in stellar evolution. In the last few years, asteroseismology has enabled the measurement of strong magnetic fields 10 ^4 –10 ^6 G in the cores of dozens of red giants and is the only known way to directly measure ...
Nicholas Z. Rui, Jim Fuller, J. M. Joel Ong   +2 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

High-cadence spectroscopy of M-dwarfs – II. Searching for stellar pulsations with HARPS [PDF]

, 2017
Stellar oscillations appear all across the Hertzsprung–Russell diagram. Recent theoretical studies support their existence also in the atmosphere of M dwarfs. These studies predict for them short periodicities ranging from 20 min to 3 h.
Z. M. Berdiñas, J. MacDonald, Barnes, J. R., Zechmeister, M, Amado, P. J., J. R. Barnes, Berdiñas, Z. M., Anglada-Escudé, G., P. J. Amado, MacDonald, J., Anglada-Escude, G, Zechmeister, M., C. Rodríguez-López, MacDonald, J, Sarmiento, LF, G. Anglada-Escudé, M. Zechmeister, Sarmiento, L. F., Barnes, JR, Rodríguez-López, C., Amado, PJ, Berdinas, ZM, L. F. Sarmiento, Rodriguez-Lopez, C   +23 more
core   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source