Results 31 to 40 of about 2,749 (261)

Differential Rotation of CoRoT Stars and a Kepler Binary Star from Starspot Transit Mapping

open access: yesThe Astrophysical Journal
While direct magnetic field measurements are rare for slowly rotating stars, spots observed during planetary transits provide a potential indicator of magnetic activity on stellar surfaces.
Adriana Valio   +2 more
doaj   +1 more source

Kepler main-sequence solar-like stars: surface rotation and magnetic-activity evolution

open access: yesFrontiers in Astronomy and Space Sciences
While the mission’s primary goal was focused on exoplanet detection and characterization, Kepler made and continues to make extraordinary advances in stellar physics. Stellar rotation and magnetic activity are no exceptions.
Ângela R. G. Santos   +8 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Asteroseismology and Spectropolarimetry of the Exoplanet Host Star λ Serpentis

open access: yesThe Astronomical Journal, 2023
The bright star λ Ser hosts a hot Neptune with a minimum mass of 13.6 M _⊕ and a 15.5 day orbit. It also appears to be a solar analog, with a mean rotation period of 25.8 days and surface differential rotation very similar to the Sun.
Travis S. Metcalfe   +33 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Toward a Self-consistent Hydrodynamical Model of the Solar Tachocline

open access: yesThe Astrophysical Journal
The solar tachocline is a thin internal boundary layer in the Sun located between the differentially rotating convection zone and the uniformly rotating region of the radiative interior beneath. E. A. Spiegel & J. P.
P. Garaud, D. O. Gough, L. I. Matilsky
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

The California-Kepler Survey. XI. A Survey of Chromospheric Activity through the Lens of Precise Stellar Properties

open access: yesThe Astrophysical Journal
Surveys of exoplanet host stars are valuable tools for assessing population level trends in exoplanets, and their outputs can include stellar ages, activity, and rotation periods.
Howard Isaacson   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Relationship of Stellar Radius Inflation to Rotation and Magnetic Starspots at 10–670 Myr

open access: yesThe Astrophysical Journal Letters
Active, low-mass stars are widely observed to have radii that are larger than predicted by standard stellar models. Proposed mechanisms for this radius inflation generally involve stellar magnetism, either in the form of added pressure support in the ...
Lyra Cao, Keivan G. Stassun
doaj   +1 more source

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