Results 41 to 50 of about 2,749 (261)

The rotation–magnetism relationship in solar-type stars

Astronomy & Astrophysics
Context. The rotation–activity relationship of G-type stars results from surface magnetic fields emerging from the interior. How the magnetic flux and its emergence rate scale with rotation rate are not well understood, both observationally and ...
Işık Emre, Solanki Sami K., Krivova Natalie A., Shapiro Alexander I.   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Meta-analysis of Photometric and Asteroseismic Measurements of Stellar Rotation Periods: The Lomb–Scargle Periodogram, Autocorrelation Function, and Wavelet and Rotational Splitting Analysis for 92 Kepler Asteroseismic Targets

The Astrophysical Journal, 2022
We perform intensity variability analyses (photometric analyses: the Lomb–Scargle periodogram, autocorrelation, and wavelet) and asteroseismic analysis of 92 Kepler solar-like main-sequence stars to understand the reliability of the measured stellar ...
Yuting Lu, Othman Benomar, Shoya Kamiaka, Yasushi Suto   +3 more
doaj   +1 more source

Stellar ages and stellar rotation

, 2016
Stellar ages will play a big role in the next generation of astronomy. Useful to exoplaneteers and galactic archaeologists alike, this relatively under-exploited stellar property is currently limited by the precision of dating techniques. The work presented in this thesis contributes incrementally to a greater understanding of rotation period decay in ...
openaire   +2 more sources

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Quiet Please: Detrending Radial Velocity Variations from Stellar Activity with a Physically Motivated Spot Model

The Astronomical Journal
For solar-type stars, spots and their associated magnetic regions induce radial velocity perturbations through the Doppler rotation signal and the suppression of convective blueshift, collectively known as rotation modulation.
Jared C. Siegel, Samuel Halverson, Jacob K. Luhn, Lily L. Zhao, Khaled Al Moulla, Paul Robertson, Chad F. Bender, Ryan C. Terrien, Arpita Roy, Suvrath Mahadevan, Fred Hearty, Joe P. Ninan, Jason T. Wright, Eric B. Ford, Christian Schwab, Guðmundur Stefánsson, Cullen H. Blake, Michael W. McElwain   +17 more
doaj   +1 more source

Rotation and Stellar Evolution [PDF]

Symposium - International Astronomical Union, 1981
Does rotation influence stellar evolution? Does it cause observational effects other than line broadening? Can rotation be responsible for mixing of chemical elements throughout the star? Do evolved stars have rapidly rotating cores? This, for instance, is of interest if one wants to compute the details of supernova events.
R. Kippenhahn, H.-C. Thomas
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Stellar Cycle Variability in Mount Wilson Stars and Dynamo Models: Rotation Rate and Dynamo Number Dependency

The Astrophysical Journal
Similar to the solar cycle, the magnetic cycles of other solar-type stars are also variable. How the variability of the stellar cycle changes with the rotation rate or the dynamo number is valuable information for understanding the stellar dynamo process.
Suyog Garg, Rohan B. Mandrai, Bidya Binay Karak   +2 more
doaj   +1 more source