Results 61 to 70 of about 578,030 (294)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Asteroseismology and Spectropolarimetry of the Exoplanet Host Star λ Serpentis

The Astronomical Journal, 2023
The bright star λ Ser hosts a hot Neptune with a minimum mass of 13.6 M _⊕ and a 15.5 day orbit. It also appears to be a solar analog, with a mean rotation period of 25.8 days and surface differential rotation very similar to the Sun.
Travis S. Metcalfe, Derek Buzasi, Daniel Huber, Marc H. Pinsonneault, Jennifer L. van Saders, Thomas R. Ayres, Sarbani Basu, Jeremy J. Drake, Ricky Egeland, Oleg Kochukhov, Pascal Petit, Steven H. Saar, Victor See, Keivan G. Stassun, Yaguang Li, Timothy R. Bedding, Sylvain N. Breton, Adam J. Finley, Rafael A. García, Hans Kjeldsen, Martin B. Nielsen, J. M. Joel Ong, Jakob L. Rørsted, Amalie Stokholm, Mark L. Winther, Catherine A. Clark, Diego Godoy-Rivera, Ilya V. Ilyin, Klaus G. Strassmeier, Sandra V. Jeffers, Stephen C. Marsden, Aline A. Vidotto, Sallie Baliunas, Willie Soon   +33 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Toward a Self-consistent Hydrodynamical Model of the Solar Tachocline

The Astrophysical Journal
The solar tachocline is a thin internal boundary layer in the Sun located between the differentially rotating convection zone and the uniformly rotating region of the radiative interior beneath. E. A. Spiegel & J. P.
P. Garaud, D. O. Gough, L. I. Matilsky
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Relationship of Stellar Radius Inflation to Rotation and Magnetic Starspots at 10–670 Myr

The Astrophysical Journal Letters
Active, low-mass stars are widely observed to have radii that are larger than predicted by standard stellar models. Proposed mechanisms for this radius inflation generally involve stellar magnetism, either in the form of added pressure support in the ...
Lyra Cao, Keivan G. Stassun
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The California-Kepler Survey. XI. A Survey of Chromospheric Activity through the Lens of Precise Stellar Properties

The Astrophysical Journal
Surveys of exoplanet host stars are valuable tools for assessing population level trends in exoplanets, and their outputs can include stellar ages, activity, and rotation periods.
Howard Isaacson, Stephen R. Kane, Brad Carter, Andrew W. Howard, Lauren Weiss, Erik A. Petigura, Benjamin Fulton   +6 more
doaj   +1 more source

The rotation–magnetism relationship in solar-type stars

Astronomy & Astrophysics
Context. The rotation–activity relationship of G-type stars results from surface magnetic fields emerging from the interior. How the magnetic flux and its emergence rate scale with rotation rate are not well understood, both observationally and ...
Işık Emre, Solanki Sami K., Krivova Natalie A., Shapiro Alexander I.   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source