YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Proton Acceleration in Colliding Stellar Wind Binaries [PDF]
, 2019 Emanuele Grimaldo +9 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Rotational Evolution of Classical T Tauri Stars: Models and Observations
The Astrophysical JournalWe developed a grid of stellar rotation models for low-mass and solar-type classical T Tauri stars (CTTS; 0.3 M _⊙ < M _* < 1.2 M _⊙ ). These models incorporate the star–disk interaction and magnetospheric ejections to investigate the evolution of the ...
Javier Serna +19 more
doaj +1 more source
The galactic mass injection from cool stellar winds of the 1 to 2.5 ${\vec M}_{\odot}$ stars in the solar neighbourhood [PDF]
, 2001 K.‐P. Schröder, E. Sedlmayr
openalex +1 more source
Effect of mass-loss due to stellar winds on the formation of supermassive black hole seeds in dense nuclear star clusters [PDF]
, 2021 Arpan Das +3 more
openalex +1 more source
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
Colliding wind binaries and gamma-ray binaries : relativistic version of the RAMSES code
, 2012 Gamma-ray binaries are colliding wind binaries (CWB) composed of a massive star a non-accreting pulsar with a highly relativistic wind. Particle acceleration at the shocks results in emission going from extended radio emission to the gamma-ray band.
Dubus, Guillaume +3 more
core +1 more source
Weakened Magnetic Braking Signals the Collapse of the Global Stellar Dynamo
The Astrophysical Journal LettersWeakened magnetic braking (WMB) was originally proposed in 2016 to explain anomalously rapid rotation in old field stars observed by the Kepler mission.
Travis S. Metcalfe +9 more
doaj +1 more source
Simulating the Interaction of a Non-magnetized Planet with the Stellar Wind Produced by a Sun-like Star Using the FLASH Code [PDF]
, 2019 Edgard F. D. Evangelista +7 more
openalex +1 more source