Results 41 to 50 of about 65,066 (300)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The Astrophysical Journal, 2022 We perform three-dimensional (3D) magnetohydrodynamic simulations of magnetospheric accretion in a T Tauri star to study the accretion and wind structures in the close vicinity of the star.
Shinsuke Takasao +3 more
doaj +1 more source
X-ray diagnostics of massive star winds
, 2016 Nearly all types of massive stars with radiatively driven stellar winds are X-ray sources that can be observed by the presently operating powerful X-ray telescopes.
Oskinova, Lidia
core +1 more source
On fan-shaped cold MHD winds from Keplerian accretion discs [PDF]
, 2012 We investigate under which conditions cold, fan-shaped winds can be steadily launched from thin (Keplerian) accretion discs. Such winds are magneto-centrifugal winds launched from a thin annulus in the disc, along open magnetic field lines that fan out ...
Casse, Fabien, Ferreira, Jonathan
core +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Wind-fed Supermassive Black Hole Accretion in the Ultracompact Dwarf Galaxy M60-UCD1
The Astrophysical JournalUltracompact dwarf galaxies (UCDs) are thought to be remnants of stripped galactic nuclei, among which a handful are known to host a central supermassive black hole (SMBH).
Zhao Su, Zhiyuan Li, Meicun Hou
doaj +1 more source
UniverseThere have been many research works involving mass transfer in stellar binaries, all of which are limited to certain systems with specific binary parameters.
Bushra Ata Ali +2 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source