Results 61 to 70 of about 5,969 (301)
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud
The Astrophysical Journal LettersDetermining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román +12 more
doaj +1 more source
Highlights of Astronomy, 1980 The term stellar wind is used nowadays to describe any more or less continuous mass loss from a star. With the observations made with satellites in recent years it is becoming clear that most stars are undergoing this form of mass loss, though its magnitude can be very different from one star to another.
openaire +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Stellar winds can affect gas dynamics in debris disks and create observable belt winds
, 2022 Context: Gas is now detected in many extrasolar systems around mature stars aged between 10 Myr to $\sim$ 1 Gyr with planetesimal belts. Gas in these mature disks is thought to be released from planetesimals and has been modelled using a viscous disk ...
Pringle, J. +11 more
core +1 more source
, 2023 <p>Version 1.4.5 of <code>p-winds</code> improves documentation and changes the way that MUSCLES spectra are handled. Here is the changelog:</p> <ul> <li>Added almost all MUSCLES, Mega-MUSCLES and MUSCLES Extension ...
Dos Santos, Leonardo A. +1 more
core +2 more sources
Detection of Metal Enrichment by SN 2011jm in NGC 4809
The Astrophysical Journal LettersCosmic metals are believed to originate from stellar and supernovae (SNe) nucleosynthesis, dispersed into the interstellar medium (ISM) through stellar winds and supernova explosions.
Yulong Gao +4 more
doaj +1 more source
Critical Metallicity of Cool Supergiant Formation. I. Effects on Stellar-mass Loss and Feedback
The Astrophysical Journal, 2023 This paper systematically studies the relation between metallicity and mass loss of massive stars. We perform one-dimensional stellar evolution simulations and build a grid of ∼2000 models with initial masses ranging between 11 and 60 M _⊙ and absolute ...
Po-Sheng Ou +3 more
doaj +1 more source