Results 61 to 70 of about 65,066 (300)

O VI in Stellar Winds [PDF]

open access: yesSymposium - International Astronomical Union, 1979
The region of the O VI resonance doublet around 1030 Å has been observed in 9 stars with the high resolution (0.051 Å FWHM) detector on the Copernicus satellite spectrometer. Although the spectra are confused with interstellar Lyman β and H2 absorption, P Cygni profiles or shifted absorption lines indicating mass flow were found in ζ Pup (O4If), 15 Mon
openaire   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Stellar Winds on the Main-Sequence II: the Evolution of Rotation and Winds

open access: yes, 2015
Aims: We study the evolution of stellar rotation and wind properties for low-mass main-sequence stars. Our aim is to use rotational evolution models to constrain the mass loss rates in stellar winds and to predict how their properties evolve with time on
Brott, I.   +3 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

JWST/NIRCam Imaging of the Bipolar Planetary Nebula NGC 6537: The (Infra)red Spider, Revealed

open access: yesThe Astrophysical Journal
We present James Webb Space Telescope (JWST) Near-Infrared Camera (NIRCam) Br α , H _2 , [Fe ii ], and polycyclic aromatic hydrocarbon (PAH) imaging of the molecule-rich, high-excitation bipolar planetary nebula (PN) NGC 6537 (the Red Spider ...
Joel H. Kastner   +7 more
doaj   +1 more source

Wind-Blanketed Stellar Atmospheres [PDF]

open access: yesSymposium - International Astronomical Union, 1983
Radiation scattered by a stellar wind back into the photosphere alters the temperature-depth relation and thus the stellar flux distribution. The fraction of the radiation returned to the star at every wavelength has been calculated using stellar wind models accounting for approximately 10 000 lines.
D.C. Abbott, D.G. Hummer
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Investigating the Nested Structure of the Outflow from the Low Luminosity Protostar IRAS 16253-2429 Using JWST and ALMA

open access: yesThe Astrophysical Journal
Understanding the earliest stage of star and planet formation requires detailed observations to address the connection and interplay between the accretion, outflow, and disk evolution.
Mayank Narang   +39 more
doaj   +1 more source

Magnetic Braking Formulation for Sun-Like Stars: Dependence on Dipole Field Strength and Rotation Rate [PDF]

open access: yes, 2012
We use two-dimensional axisymmetric magnetohydrodynamic simulations to compute steady-state solutions for solar-like stellar winds from rotating stars with dipolar magnetic fields.
Barnes   +20 more
core   +4 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

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