Results 61 to 70 of about 65,066 (300)
The region of the O VI resonance doublet around 1030 Å has been observed in 9 stars with the high resolution (0.051 Å FWHM) detector on the Copernicus satellite spectrometer. Although the spectra are confused with interstellar Lyman β and H2 absorption, P Cygni profiles or shifted absorption lines indicating mass flow were found in ζ Pup (O4If), 15 Mon
openaire +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Stellar Winds on the Main-Sequence II: the Evolution of Rotation and Winds
Aims: We study the evolution of stellar rotation and wind properties for low-mass main-sequence stars. Our aim is to use rotational evolution models to constrain the mass loss rates in stellar winds and to predict how their properties evolve with time on
Brott, I. +3 more
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
JWST/NIRCam Imaging of the Bipolar Planetary Nebula NGC 6537: The (Infra)red Spider, Revealed
We present James Webb Space Telescope (JWST) Near-Infrared Camera (NIRCam) Br α , H _2 , [Fe ii ], and polycyclic aromatic hydrocarbon (PAH) imaging of the molecule-rich, high-excitation bipolar planetary nebula (PN) NGC 6537 (the Red Spider ...
Joel H. Kastner +7 more
doaj +1 more source
Wind-Blanketed Stellar Atmospheres [PDF]
Radiation scattered by a stellar wind back into the photosphere alters the temperature-depth relation and thus the stellar flux distribution. The fraction of the radiation returned to the star at every wavelength has been calculated using stellar wind models accounting for approximately 10 000 lines.
D.C. Abbott, D.G. Hummer
openaire +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Understanding the earliest stage of star and planet formation requires detailed observations to address the connection and interplay between the accretion, outflow, and disk evolution.
Mayank Narang +39 more
doaj +1 more source
Magnetic Braking Formulation for Sun-Like Stars: Dependence on Dipole Field Strength and Rotation Rate [PDF]
We use two-dimensional axisymmetric magnetohydrodynamic simulations to compute steady-state solutions for solar-like stellar winds from rotating stars with dipolar magnetic fields.
Barnes +20 more
core +4 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source

