Results 71 to 80 of about 5,969 (301)
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
, 2013 Classical T Tauri stars are low mass young forming stars that are surrounded by a circumstellar accretion disc from which they gain mass. Despite this accretion and their own contraction that should both lead to their spin up, these stars seem to ...
J. Ferreira
core +1 more source
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Solar and stellar coronae and winds
, 2016 Solar-like stars influence their environments through their coronal emis- sion and winds. These processes are linked through the physics of the stellar magnetic field, whose strength and geometry has now been explored for a large number of stars through ...
Moira Jardine
core +1 more source
JWST/NIRCam Imaging of the Bipolar Planetary Nebula NGC 6537: The (Infra)red Spider, Revealed
The Astrophysical JournalWe present James Webb Space Telescope (JWST) Near-Infrared Camera (NIRCam) Br α , H _2 , [Fe ii ], and polycyclic aromatic hydrocarbon (PAH) imaging of the molecule-rich, high-excitation bipolar planetary nebula (PN) NGC 6537 (the Red Spider ...
Joel H. Kastner +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2015 In this paper, we summarize the basic properties of radiative stellar winds from the theoretical and observational point of views. We illustrate two examples of a radiative code applied to stellar physics: the SIMECA code successfully used to constrain ...
Ph. Stee, O. Chesneau
core +1 more source
The Astrophysical JournalUnderstanding the earliest stage of star and planet formation requires detailed observations to address the connection and interplay between the accretion, outflow, and disk evolution.
Mayank Narang +39 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Spin-down of Solar-mass Protostars in Magnetospheric Accretion Paradigm
The Astrophysical JournalStellar spin is one of the fundamental quantities that characterize a star itself and its planetary system. Nevertheless, stellar spin-down mechanisms in protostellar and pre-main-sequence stellar phases have been a long-standing problem in star ...
Shinsuke Takasao +4 more
doaj +1 more source