Results 51 to 60 of about 242,475 (295)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Astrophysical Journal, 2023 Many of the short-lived radioactive nuclei that were present in the early solar system can be produced in massive stars. In the first paper in this series, we focused on the production of ^26 Al in massive binaries.
Hannah E. Brinkman +4 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Wind-fed Supermassive Black Hole Accretion in the Ultracompact Dwarf Galaxy M60-UCD1
The Astrophysical JournalUltracompact dwarf galaxies (UCDs) are thought to be remnants of stripped galactic nuclei, among which a handful are known to host a central supermassive black hole (SMBH).
Zhao Su, Zhiyuan Li, Meicun Hou
doaj +1 more source
UniverseThere have been many research works involving mass transfer in stellar binaries, all of which are limited to certain systems with specific binary parameters.
Bushra Ata Ali +2 more
doaj +1 more source
Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The Astrophysical Journal, 2022 We perform three-dimensional (3D) magnetohydrodynamic simulations of magnetospheric accretion in a T Tauri star to study the accretion and wind structures in the close vicinity of the star.
Shinsuke Takasao +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
First JWST/NIRSpec Spectroscopy of O Stars in the Small Magellanic Cloud
The Astrophysical Journal LettersDetermining how much mass is removed by stellar winds is crucial to understanding massive star evolution and feedback. However, traditional spectroscopic diagnostics in the UV and optical are not sensitive enough to characterize weak stellar winds of OB ...
Armin Mang Román +12 more
doaj +1 more source