Results 81 to 90 of about 5,969 (301)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Impact of Wolf-Rayet stellar winds on compact object formation [PDF]

open access: yes
openWolf-Rayet (WR) stars are massive stars that have lost their hydrogen envelopes, exposing the underlying helium cores. In the Small Magellanic Cloud (SMC), 12 WR stars have been observed, 7 of which appear to be single.
MESINI, SOFIA
core  

Clumping in stellar winds and interiors

open access: yes, 2016
The uncertain clumping properties pose a major problem for the quantitative analysis and the modelling of hot star winds. New results suggest that also the outer envelopes of massive stars may be affected by clumping, with important consequences for ...
Götz Gräfener
core   +1 more source

Molecules in Stellar Winds [PDF]

open access: yesSymposium - International Astronomical Union, 1992
High mass-loss molecular winds are characterstic of two important phases of stellar evolution, very young protostars and stars on the asymptotic branch. Novel chemical processes in these winds suggest a variety of new astronomical observations.
openaire   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Microlensing of circumstellar envelopes III. Line profiles from stellar winds in homologous expansion [PDF]

open access: yes, 2006
This paper examines line profile evolution due to the linear expansion of circumstellar material obsverved during a microlensing event. This work extends our previous papers on emission line profile evolution from radial and azimuthal flow during point ...
Bryce, H.M.   +8 more
core   +1 more source

An Embedded Disk (eDisk) in the IceAge: Investigating the Jet and Outflow from Ced 110 IRS4

open access: yesThe Astronomical Journal
We present a comprehensive study of the large-scale structure, jet and outflow morphology, and kinematics of the Class 0/I protostellar binary Ced 110 IRS4, using JWST NIRCam (F150W and F410M) and MIRI MRS observations from the JWST ERC program IceAge ...
Mayank Narang   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Young Stellar Clusters with a Schuster Mass Distribution - I: Stationary Winds

open access: yes, 2013
Hydrodynamic models for spherically-symmetric winds driven by young stellar clusters with a generalized Schuster stellar density profile are explored. For this we use both semi-analytic models and 1D numerical simulations.
GUILLERMO TENORIO TAGLE   +2 more
core  

The interaction of multiple stellar winds in stellar clusters: potential flow

open access: yes, 2018
Context. While several studies have investigated large-scale cluster winds resulting from an intra-cluster interaction of multiple stellar winds, as yet they have not provided details of the bordering flows inside a given cluster. Aims.
A. Noack   +4 more
core   +1 more source

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