Results 41 to 50 of about 1,165,162 (267)
Improving cellular fitness of human stem cell-derived islets under hypoxia
Nature CommunicationsStem cell-derived islet cell therapy can effectively treat type 1 diabetes, but its efficacy is hindered by low oxygen supply post-transplantation, particularly in subcutaneous spaces and encapsulation devices, leading to cell dysfunction.
Xi Wang +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla +6 more
wiley +1 more source
Stem-cell ecology and stem cells in motion
Blood, 2008 Abstract This review highlights major scientific developments over the past 50 years or so in concepts related to stem-cell ecology and to stem cells in motion. Many thorough and eloquent reviews have been presented in the last 5 years updating progress in these issues.
Thalia, Papayannopoulou +1 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko +19 more
wiley +1 more source
Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, 2019 A stem cell is an undifferentiated cell that can self-renew itself and can commit to a specific cell type. Depending on their residency, stem cells are classified into two main categories as embryonic stem cells and adult stem cells. According to their differentiation and developmental potential, stem cells may be classified as totipotent, pluripotent,
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Results of COG ANBL1221 changed treatment paradigms for patients with relapsed/refractory neuroblastoma. Chemoimmunotherapy with irinotecan/temozolomide/dinutuximab is now used as both bridge therapy following suboptimal response to induction and as treatment in first relapse.
Elizabeth Sokol +6 more
wiley +1 more source
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis
Nature Communications, 2019 LncRNA loci potentially contain multiple modes that can exert function, including DNA regulatory elements. Here, the authors generated genetic models in mice to dissect the role of the syntenically conserved lncRNA Firre in the context of hematopoiesis.
Jordan P. Lewandowski +14 more
doaj +1 more source
Generation of pancreatic β cells for treatment of diabetes: advances and challenges
Stem Cell Research & Therapy, 2018 Human embryonic stem cells (hESC) and induced pluripotent stem cells (hiPSC) are considered attractive sources of pancreatic β cells and islet organoids.
Hussain Md. Shahjalal +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source
Creation of a cell culture bank: experience of the Pokrovsky Cell Technology Center
Кардиоваскулярная терапия и профилактикаModern research in cell biology places high demands on the model objects used, including cell cultures. These requirements are dictated by the need to avoid artifacts in work and reduce potential risks to the environment associated with biological hazard.
E. M. Prikhodko +8 more
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