Results 31 to 40 of about 6,619,392 (208)

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]

, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Polgár, Zsuzsanna, Varga, Eszter, Klincumhom, Nuttha, Dinnyés, András, Nemes, Csilla, Pirity, Melinda K.   +5 more
core   +1 more source

Forces in stem cells and cancer stem cells

Cells & Development, 2022
Endogenous and exogenous forces are critical in physiology and pathology of the human body. Increasing evidence suggests that these forces, mechanics, and force-associated signaling are essential in regulating functions of living cells. Here we review advances in understanding the impact of forces and mechanics on functions and fate of embryonic stem ...
Farhan, Chowdhury, Bo, Huang, Ning, Wang
openaire   +2 more sources

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse [PDF]

, 2011
A frequent complication in colorectal cancer (CRC) is regeneration of the tumor after therapy. Here, we report that a gene signature specific for adult intestinal stem cells (ISCs) predicts disease relapse in CRC patients.
Merlos-Suárez, Anna, Sancho, Elena, Munoz, P., Clevers, Hans, Barriga de Vicente, Francisco Martín, 1983-, Rossell, D., Mangues, Ramón, Marta Sevillano, David Rossell, Xavier Hernando-Momblona, Muñoz, Purificación, Batlle Gómez, Eduard, Sevillano, M., Victoria da Silva-Diz, Hans Clevers, María Virtudes Céspedes, Rossell, David, Sevillano, Marta, Merlos-Suarez, A., Céspedes, María Virtudes, da Silva-Diz, V., Silva-Diz, Victoria da, Sancho, E., Iglesias, M., Clevers, H., Mar Iglesias, Eduard Batlle, Barriga, F.M., Jung, Peter, Purificación Muñoz, Peter Jung, Hernando-Momblona, Xavier, da Silva-Diz, Victoria, Iglesias, Mar, Hernando-Momblona, X., Francisco M. Barriga, Iglesias Coma, Mar, Jung, P., Cespedes, M.V., Anna Merlos-Suárez, Batlle, E., Barriga, Francisco M., Batlle, Eduard, Elena Sancho, Mangues, R., Ramón Mangues   +45 more
core   +1 more source

Stem cells: the intestinal stem cell as a paradigm [PDF]

Carcinogenesis, 2000
Stem cell research provides a foundation for therapeutic advancement in oncology, clinical genetics and a diverse array of degenerative disorders. For example, the elucidation of pathways governing proliferative regulation and differentiation within cellular systems will result in medical strategies aimed at the root cause of cancer.
S P, Bach, A G, Renehan, C S, Potten
openaire   +2 more sources

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes [PDF]

, 2014
Standard culture of human induced pluripotent stem cells (hiPSCs) requires basic Fibroblast Growth Factor (bFGF) to maintain the pluripotent state, whereas hiPSC more closely resemble epiblast stem cells than true naïve state ES which requires LIF to ...
Tang, D, Suzuki, H., Forrest, Alistair R. R., Hasegawa, Y., Suzuki, H, Ovchinnikov, Dmitry A., Hitchens, Kelly J., Takahashi, N., Forrest, A.R.R., Kenna, Tony, Suzuki, Harukazu, Tang, D., Joshi, Anagha, Hayashizaki, Y., Wolvetang, Ernst, Tang, Dave, Suzuki, H., Forrest, Alistair R R, FANTOM Consortium, the FANTOM consortium, Vijayan, Dipti, Wells, Christine A., Hasegawa, Y, Hayashizaki, Yoshihide, Forrest, ARR, Takahashi, Naoko, Briggs, James, Hasegawa, Yuki, Blumenthal, Antje, Tang, D., Hayashizaki, Y, ?, ?, Sajantila, Antti, Hasegawa, Y., Takahashi, N, Takahashi, N., Forrest, A. R., Beckhouse, Anthony G., FANTOM Consortium,, Hayashizaki, Y.   +39 more
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Understanding the regulatory mechanisms of endometrial cells on activities of endometrial mesenchymal stem-like cells during menstruation [PDF]

, 2020
Background: The identification of endometrial stem/progenitor cells in a high turnover rate tissue suggests that a well-orchestrated underlying network controls the behaviour of these stem cells. The thickness of the endometrium can grow from 0.5-1 mm to
Ng, Ernest H Y, Chan, RWS, Chan, Rachel W S, Xu, Shan, Yeung, William S B, Li, T, Li, Tianqi, Ng, EHY, Yeung, WSB, Xu, S   +9 more
core   +1 more source

Treatment of shoulder osteoarthritis and rotator cuff tears with bone marrow concentrate and whole bone marrow injections

Cogent Medicine, 2019
Background: Human bone marrow has shown promise as a minimally invasive approach in treating a variety of musculoskeletal conditions due to the presence of stem cells, platelets, and growth factors in solution.
Marc Darrow, Brent Shaw, Nicholas Schmidt, Gabrielle Boeger, Saskia Budgett   +4 more
doaj   +1 more source

Stem cells, cancer, and cancer stem cells [PDF]

Nature, 2001
Stem cell biology has come of age. Unequivocal proof that stem cells exist in the haematopoietic system has given way to the prospective isolation of several tissue-specific stem and progenitor cells, the initial delineation of their properties and expressed genetic programmes, and the beginnings of their utility in regenerative medicine.
Reya, T., Morrison, Sean J., Clarke, Michael. F., Weissman, Irving L.   +3 more
openaire   +3 more sources

The Choice of Anticoagulant Influences the Characteristics of Bone Marrow Aspirate Concentrate and Mesenchymal Stem Cell Bioactivity In Vitro

Stem Cells International, 2022
Bone marrow aspirate concentrate (BMC) is commonly used as a therapeutic agent to resolve orthopedic injuries, using its unique cellularity to reduce inflammation and prime the region for repair.
Ryan C. Dregalla, Jessica Ann Herrera, Lucanus Steven Koldewyn, Edward Jeffery Donner   +3 more
doaj   +1 more source

Stem cell growth and differentiation in Hydra attenuata [PDF]

, 1979
Interstitial stem cells in Hydra are rapidly proliferating multipotent stem cells which continuously give rise to precursors for nerve and nematocyte differentiation.
Sproull, Frederick, David, Charles N.
core   +3 more sources