Results 31 to 40 of about 15,064,991 (360)

Treatment of unresolved lower back pain with platelet-rich plasma injections

open access: yesCogent Medicine, 2019
Background: Platelet-Rich Plasma (PRP) is a non-invasive modality that has been used to treat musculoskeletal conditions for the past two decades. Based on our research, there were no publications that studied the effect of PRP on unresloved lower back ...
Marc Darrow   +4 more
doaj   +1 more source

Integrating deep learning and unbiased automated high-content screening to identify complex disease signatures in human fibroblasts

open access: yesNature Communications, 2022
By coupling robotic cell culture systems with artificial intelligence–powered image analysis, Schiff et al. identify previously unseen characteristics of Parkinson’s disease in patient skin cells that distinguish them from healthy controls.
Lauren Schiff   +42 more
doaj   +1 more source

Distribution of interstitial stem cells in Hydra [PDF]

open access: yes, 1979
The distribution of interstitial stem cells along the Hydra body column was determined using a simplified cloning assay. The assay measures stem cells as clone-forming units (CFU) in aggregates of nitrogen mustard inactivated Hydra tissue.
Bode   +16 more
core   +2 more sources

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

open access: yesStem cell research & therapeutics, 2019
Normal wound healing is a dynamic and complex multiple phase process involving coordinated interactions between growth factors, cytokines, chemokines, and various cells. Any failure in these phases may lead wounds to become chronic and have abnormal scar
Azar Nourian Dehkordi   +3 more
semanticscholar   +1 more source

Prostate Stem Cells and Cancer Stem Cells [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Stem/progenitor cells play central roles in processes of organogenesis and tissue maintenance, whereas cancer stem cells (CSCs) are thought to drive tumor malignancy. Here, we review recent progress in the identification and analysis of normal prostate stem/progenitor cells as well as putative CSCs in both genetically engineered mouse models as well as
Jia J, Li, Michael M, Shen
openaire   +2 more sources

Nitric oxide has contrasting age-dependent effects on the functionality of murine hematopoietic stem cells

open access: yesStem Cell Research & Therapy, 2016
Background The success of hematopoietic stem cell (HSC) transplantation is dependent on the quality of the donor HSCs. Some sources of HSCs display reduced engraftment efficiency either because of inadequate number (e.g., fetal liver and cord blood), or ...
Sapana Jalnapurkar   +4 more
doaj   +1 more source

Challenges and Controversies in Human Mesenchymal Stem Cell Therapy

open access: yesStem Cells International, 2019
Stem cell therapy is being intensely investigated within the last years. Expectations are high regarding mesenchymal stem cell (MSC) treatment in translational medicine. However, many aspects concerning MSC therapy should be profoundly defined.
B. Lukomska   +5 more
semanticscholar   +1 more source

Embryonic stem cell-derived hematopoietic stem cells [PDF]

open access: yesProceedings of the National Academy of Sciences, 2005
Despite two decades of studies documenting thein vitroblood-forming potential of murine embryonic stem cells (ESCs), achieving stable long-term blood engraftment of ESC-derived hematopoietic stem cells in irradiated mice has proven difficult. We have exploited theCdx-Hoxpathway, a genetic program important for blood development, to enhance the ...
Yuan, Wang   +4 more
openaire   +2 more sources

MicroRNAs as Important Regulators Mediate the Multiple Differentiation of Mesenchymal Stromal Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
MicroRNAs (miRNAs) are endogenous short non-encoding RNAs which play a critical role on the output of the proteins, and influence multiple biological characteristics of the cells and physiological processes in the body.
Chao Yang   +5 more
doaj   +1 more source

Do high-volume centers really save more lives? A call for scientific rigor and transparency. Response to Comment on: Does size matter? Center-specific characteristics and survival after allogeneic hematopoietic cell transplantation for acute myeloid leukemia: an analysis of the German Registry for Stem Cell Transplantation and Cell Therapy

open access: yesHaematologica
Not available.
Wolfgang Bethge   +2 more
doaj   +1 more source

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