Results 11 to 20 of about 15,064,991 (360)

Mechanical forces direct stem cell behaviour in development and regeneration

Nature Reviews Molecular Cell Biology, 2017
K. Vining, D. Mooney
semanticscholar   +3 more sources

Haematopoietic stem cell activity and interactions with the niche

Nature Reviews Molecular Cell Biology, 2019
Sandra Pinho, P. Frenette
semanticscholar   +3 more sources

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

Scientific Reports, 2020
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro, Valérie Lang, Izaskun Ferrin, Jon Fernández-Rueda, Lorea Zabaleta, Estibaliz Pérez-Ruiz, Pilar Sepúlveda, César Trigueros   +7 more
doaj   +1 more source

Institutional imaginaries of publics in stem cell banking: The cases of the UK and Spain [PDF]

, 2013
The UK and Spanish Stem Cell Banks hold politically controversial-but potentially therapeutically beneficial-human embryonic stem cells for distribution to research laboratories globally.
Bharawaj A., Hooper J., Jasanoff S., Neil Stephens, Paul Atkinson, Peter Glasner, Steering Committee for the UK Stem Cell Bank and For the Use of Stem Cell Lines, Steering Committee for the UK Stem Cell Bank and For the Use of Stem Cell Lines, Stem Cell Research Select Committee   +8 more
core   +2 more sources

Pluripotent Stem Cell-Based Cell Therapy-Promise and Challenges.

Cell Stem Cell, 2020
Human pluripotent stem cells such as embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) provide unprecedented opportunities for cell therapies against intractable diseases and injuries.
S. Yamanaka
semanticscholar   +1 more source

Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil [PDF]

, 2018
Purpose of Review: This review summarizes the role of hypoxia and hypoxia-inducible factors (HIFs) in the regulation of stem cell biology, specifically focusing on maintenance, differentiation, and stress responses in the context of several stem cell ...
Aljoufi, Arafat, Broxmeyer, Hal E., Huang, Xinxin, Trinh, Thao   +3 more
core   +1 more source

The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. [PDF]

, 2019
Metabolic reprogramming is an active regulator of stem cell fate choices, and successful stem cell differentiation in different compartments requires the induction of oxidative phosphorylation.
Cunningham, Thomas J, Dall'Agnese, Alessandra, Duester, Gregg, Etxaniz, Usue, Latella, Lucia, Nicoletti, Chiara, Puri, Pier Lorenzo, Sacco, Alessandra, Sala, David, Stec, Michael J   +9 more
core   +3 more sources

Assessment of established techniques to determine developmental and malignant potential of human pluripotent stem cells

Nature Communications, 2018
The International Stem Cell Initiative tests methods in a multisite study to detect pluripotency and teratoma formation (PluriTest, Embryoid Body and Teratoma methods) in human pluripotent stem cells.
The International Stem Cell Initiative
doaj   +1 more source

Mesenchymal stem cell perspective: cell biology to clinical progress

npj Regenerative Medicine, 2019
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/progenitor cells commonly referred to as mesenchymal stem cells, multipotential stromal cells, mesenchymal stromal cells, and ...
M. Pittenger, D. Discher, B. Péault, D. Phinney, J. Hare, A. Caplan   +5 more
semanticscholar   +1 more source

Proliferation versus Differentiation: Redefining Retinoic Acids Role. [PDF]

, 2018
Retinoic acid is commonly used in culture to differentiate stem cells into neurons and has established neural differentiation functions in vivo in developing and adult organisms. In this issue of Stem Cell Reports, Mishra et al.
Mosher, Kira, SCHAFFER, David
core   +1 more source