Results 111 to 120 of about 195,985 (310)
Characterization of the effects of BTK inhibition and monocyte-produced IL-8 on the hematopoietic stem cell niche [PDF]
, 2020 Hematopoietic stem and progenitor cells (HSPCs) are multipotent stem cells that give rise to all blood cell lineages. During early zebrafish development, HSPCs interact closely with endothelial cells in an endothelial niche known as the Caudal ...
Belardo, Alexander
core
Assembly of Cell‐Seeded 3D Printed Hydrogel Modules with Perfusable Channel Networks
Advanced Functional Materials, EarlyView.Macroscale assembly was utilized to prepare perfusable tissue constructs from individually 3D printed hydrogel modules with embedded branched channel networks and port arrays for cell seeding. Novel multi‐material bioreactors were fabricated to facilitate the gluing of individual modules and the perfusion culture of assembled modular constructs seeded ...
Zachary J. Geffert +10 more
wiley +1 more source
Advanced Functional Materials, EarlyView.This paper presents a digital microfluidics‐based technique for transferring and reconfiguring soft nanomembranes. Laser‐machined nanothin membranes are picked up, transported, and aligned via tailored surface tension and the actuation of water droplets, enabling the development of flexible electronics, the integration of functional materials on 3D ...
Quang Anh Nguyen +15 more
wiley +1 more source
G3: Genes, Genomes, Genetics, 2019 The stem cell niche, a regulatory microenvironment, houses and regulates stem cells for maintenance of tissues throughout an organism’s lifespan. While it is known that stem cell function declines with age, the role of niche cells in this decline is not ...
Yi-Teng Ke, Hwei-Jan Hsu
doaj +1 more source
Molecular Regulation and Rejuvenation of Muscle Stem (Satellite) Cell Aging [PDF]
, 2015 BACKGROUND: Age-related muscle loss leads to lack of muscle strength, resulting in reduced posture and mobility and an increased risk of falls, all of which contribute to a decrease in quality of life.
Dewi, N. M. (Nurrani) +2 more
core +3 more sources
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Numerical Methods for Two-Dimensional Stem Cell Tissue Growth. [PDF]
, 2013 Growth of developing and regenerative biological tissues of different cell types is usually driven by stem cells and their local environment. Here, we present a computational framework for continuum tissue growth models consisting of stem cells, cell ...
Nie, Qing, Ovadia, Jeremy
core +2 more sources
Advanced Healthcare Materials, EarlyView.Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim +5 more
wiley +1 more source
Stem Cell Research & Therapy, 2019 Background Injury of stem cell niches may disturb tissue homeostasis and regeneration coordinated by specific niche components. Yet, the mechanisms of stem cell niche restoration remain poorly understood.
Georgy Sagaradze +9 more
doaj +1 more source
Pvr expression regulators in equilibrium signal control and maintenance of Drosophila blood progenitors. [PDF]
, 2014 Blood progenitors within the lymph gland, a larval organ that supports hematopoiesis in Drosophila melanogaster, are maintained by integrating signals emanating from niche-like cells and those from differentiating blood cells.
Banerjee, Utpal +3 more
core +1 more source