Bridging the Gap Between Regulatory Approval and Patient Access: The Case for Insurance Coverage of Approved Allogeneic Stem Cell Therapy in Knee Osteoarthritis. [PDF]
Agarwal AK, Das G, Aggarwal P, Danda R.
europepmc +1 more source
Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans +7 more
wiley +1 more source
Efficacy and safety of stem cell therapy for dry eye disease: a systematic review and meta-analysis. [PDF]
Chen KY, Chan HC, Chan CM.
europepmc +1 more source
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari +10 more
wiley +1 more source
From Bench to Bedside: Translational Barriers in Mesenchymal Stem Cell Therapy for Intervertebral Disc Degeneration. [PDF]
Gradisnik L +3 more
europepmc +1 more source
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis +8 more
wiley +1 more source
Efficacy and safety of stem cell therapy in type 1 diabetes: A systematic review and meta-analysis of randomised controlled trials. [PDF]
Yadav J +8 more
europepmc +1 more source
Optical Detection of Cellular Signals at Material Interfaces
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren +5 more
wiley +1 more source
Bioenzymatic single-cell microencapsulation for enhanced stem Cell therapy. [PDF]
Xuan L +19 more
europepmc +1 more source
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu +5 more
wiley +1 more source

