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Stem Cell Therapy for Osteoporosis
Current Osteoporosis Reports, 2014Osteoporosis is a debilitating disease that affects millions of people worldwide. Current osteoporosis treatments are predominantly bone-resorbing drugs that are associated with several side effects. The use of stem cells for tissue regeneration has raised great hope in various fields of medicine, including musculoskeletal disorders.
Ben, Antebi, Gadi, Pelled, Dan, Gazit
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Stem cell therapy in scleroderma
Current Opinion in Rheumatology, 2002Scleroderma has a high mortality rate, especially in patients with early diffuse disease and poor prognostic features (such as high skin scores and internal organ involvement). In addition, there is no proven therapy for this disease. Finally, scleroderma has an autoimmune-related pathogenesis, particularly in early illness.
Yolanda, Braun-Moscovici +1 more
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Interventional stem cell therapy
Clinical Radiology, 2016The ability to deliver cells in appropriate doses to their targeted site of action is a well-known obstacle to optimising stem cell therapy. Systemic administration of cells results in pulmonary "trapping," which significantly decreases the number of available circulating cells to impact underlying disorders.
J D, Prologo +7 more
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Microencapsulation of Stem Cells for Therapy
2016An increasing demand to regenerate tissues from patient-derived sources has led to the development of cell-based therapies using autologous stem cells, thereby decreasing immune rejection of scaffolds coupled with allogeneic stem cells or allografts. Adult stem cells are multipotent and are readily available in tissues such as fat and bone marrow. They
Shirae K, Leslie +3 more
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Expert Opinion on Biological Therapy, 2016
Despite knowledge on the molecular basis of amyotrophic lateral sclerosis (ALS) having quickly progressed over the last few years, such discoveries have not yet translated into new therapeutics. With the advancement of stem cell technologies there is hope for stem cell therapeutics as novel treatments for ALS.We discuss in detail the therapeutic ...
Mazzini, L +4 more
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Despite knowledge on the molecular basis of amyotrophic lateral sclerosis (ALS) having quickly progressed over the last few years, such discoveries have not yet translated into new therapeutics. With the advancement of stem cell technologies there is hope for stem cell therapeutics as novel treatments for ALS.We discuss in detail the therapeutic ...
Mazzini, L +4 more
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Stem Cell Therapy for the Kidney?
American Journal of Therapeutics, 2009The kidney has a remarkable capacity to regenerate after injury, as it is not a terminally differentiated organ. This regenerative potential is somehow incomplete, however, and as the insult continues, progressive and irreversible scarring results in chronic renal disease.
Rachel, Zubko, William, Frishman
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Transamniotic Stem Cell Therapy
2019Transamniotic stem cell therapy (TRASCET) is a novel prenatal therapeutic alternative for the treatment of congenital anomalies. It is based upon the principle of augmenting the pre-existing biological role of select populations of fetal stem cells for targeted therapeutic benefit.
Stefanie P, Lazow, Dario O, Fauza
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Hematopoietic Stem Cells Therapies
Current Stem Cell Research & Therapy, 2016Stem cell-based therapies are recognized as a new way to treat various diseases and injuries, with a wide range of health benefits. The goal is to heal or replace diseased or destroyed organs or body parts with healthy new cells provided by stem cell transplantation.
Mihaela, Chivu-Economescu +1 more
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Current Opinion in Ophthalmology
Purpose of review To highlight the progress and future direction of limbal stem cell (LSC) therapies for the treatment of limbal stem cell deficiency (LSCD). Recent findings Direct LSC transplantation have demonstrated good long-term outcomes.
Clemence, Bonnet +2 more
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Purpose of review To highlight the progress and future direction of limbal stem cell (LSC) therapies for the treatment of limbal stem cell deficiency (LSCD). Recent findings Direct LSC transplantation have demonstrated good long-term outcomes.
Clemence, Bonnet +2 more
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Stem cell therapies for diabetes
Nature MedicineDiabetes has long-term, potentially severe implications for healthspan and lifespan and imposes an immense burden on global healthcare, the economy and society. Although a repertoire of medications is available to treat diabetes, these do not properly address the eventual lack of functional pancreatic beta cells that are needed to secrete insulin and ...
Juin Ting Chen +6 more
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