Results 241 to 250 of about 1,463,285 (410)

Markov Renewal Proportional Hazards is All You Need [PDF]

arXiv
Transition probability estimation plays a critical role in multi-state modeling, especially in clinical research. This paper investigates the application of semi-Markov and Markov renewal frameworks to the EBMT dataset, focusing on six clinical states encountered during hematopoietic stem cell transplantation.
arxiv  

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

Advanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan, Qianyu Li, Guoquan Yan, Yifei Qian, Wenyun Guo, Songling Li, Fan Wang, Wanjing Shang, Zijun Zhu, Di Ge, Yanan Wang, Yanfeng Liu   +11 more
wiley   +1 more source

Peripheral blood stem cell transplants for multiple myeloma: identification of favorable variables for rapid engraftment in 225 patients [PDF]

, 1995
Guido Tricot, Sundar Jagannath, David H. Vesole, J Nelson, Sharon Tindle, L.S. Miller, Bruce D. Cheson, John Crowley, Bart Barlogie   +8 more
openalex   +1 more source

Stem cell transplantation

HemaSphere, 2019
openaire   +4 more sources

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

Advanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding, Siwei Mao, Han Wu, Sijia Fang, Ni Zhen, Tianshu Chen, Jiabei Zhu, Xiaochen Tang, Xiaoyang Wang, Fenyong Sun, Guoqing Zhu, Qiuhui Pan, Ji Ma   +12 more
wiley   +1 more source

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome [PDF]

, 1999
TG Gross, M. Steinbuch, Todd E. DeFor, RS Shapiro, Philip B. McGlave, NKC Ramsay, JE Wagner, A.H. Filipovich   +7 more
openalex   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies

Advanced Science, EarlyView.
Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu, Yao Liu, Zujun Que, Bin Luo, Yun Yang, Yan Li, Zhanxia Zhang, Jianhui Tian   +7 more
wiley   +1 more source

Early stem cell transplantation for chronic lymphocytic leukaemia: a chance for cure? [PDF]

, 1998
Peter Dreger, Nils von Neuhoff, R. Kuse, Ruth Sonnen, B. Glaß, L. Uharek, Robert Schoch, H. Löffler, Norbert Schmitz   +8 more
openalex   +1 more source

Chromosome Missegregation Triggers Tumor Cell Pyroptosis and Enhances Anti‐Tumor Immunotherapy in Colorectal Cancer

Advanced Science, Volume 12, Issue 12, March 27, 2025.
Immune system disorders and chromosome missegregation are two of the major hallmarks of tumor. The relationship between tumor immune and chromosome missegregation is still unclear. This study reveals that YY2 high expression‐mediated chromosome missegregation/micronuclei formation triggers pyroptosis and CTL activation by activating AIM2/caspase‐1 ...
Wei Duan, Rendy Hosea, Lingxian Wang, Cao Ruan, Fuqiang Zhao, Jingyi Liu, Hezhao Zhao, Makoto Miyagishi, Shourong Wu, Vivi Kasim   +9 more
wiley   +1 more source