Results 171 to 180 of about 12,311,631 (363)

Statistical interpretations and new findings on Variation in Cancer Risk Among Tissues [PDF]

open access: yesarXiv, 2015
Tomasetti and Vogelstein (2015a) find that the incidence of a set of cancer types is correlated with the total number of normal stem cell divisions. Here, we separate the effects of standing stem cell number (i.e., organ or tissue size) and per stem cell lifetime replication rate. We show that each has a statistically significant and independent effect
arxiv  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Evaluation of a New Vasculature by High Resolution Light Microscopy: Primo Vessel and Node [PDF]

open access: yesarXiv, 2016
The primo vascular system is composed of nodes and vessels. The bundle of sub-vessels of the promo vessel is laid into an external jacket composed of endothelial cells. The node is heterogeneous in nature, composed of twisted sub-vessel bundles that fill up nearly the entire node volume.
arxiv  

Stem Cells

open access: yesDokuz Eylül Üniversitesi Tıp Fakültesi Dergisi, 2019
A stem cell is an undifferentiated cell that can self-renew itself and can commit to a specific cell type. Depending on their residency, stem cells are classified into two main categories as embryonic stem cells and adult stem cells. According to their differentiation and developmental potential, stem cells may be classified as totipotent, pluripotent,
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Metaboloepigenetic Regulation of Pluripotent Stem Cells

open access: yesStem Cells International, 2016
The differentiation of pluripotent stem cells is associated with extensive changes in metabolism, as well as widespread remodeling of the epigenetic landscape.
Alexandra J. Harvey   +2 more
doaj   +1 more source

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