Results 181 to 190 of about 1,379,057 (317)

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

RETRACTION: Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity

Stem Cells International
Stem Cells International
doaj   +1 more source

Correction to: Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model

Translational Psychiatry, 2023
Yanmin Luo, Qian Xiao, Jin Wang, Lin Jiang, Menglan Hu, Yanhong Jiang, Jing Tang, Xin Liang, Yingqiang Qi, Xiaoyun Dou, Yi Zhang, Chunxia Huang, Linmu Chen, Yong Tang   +13 more
doaj   +1 more source

Molecular insights into DNA damage response plasticity in glioma stem cells. [PDF]

Commun Biol
Molinari NC, Lusi V, Bianconi A, De Pasquale D, Giunti D, Fiaschi P, Cerutti E.   +6 more
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

CRABP2 upregulation in perichondral stem cells is associated with microtia. [PDF]

BMC Med Genomics
Zhang J, Chu F, Hu X, Yang X, Lei S, He L, Wu D, Lin L, Jiang H.   +8 more
europepmc   +1 more source

Myogenic potential of human circulating AC133+ stem cells in murine dystrophic skeletal muscle

, 2005
F. Pisati, G. Cossu, R. Bottinelli, N. Bresolin, D. Furling, V. Mouly, G. S. Butler Browne, M. Belicchi, M. Sanpaolesi, L. Porretti, K. Mamchaoui, M. Gavina, Y. Torrente, G. D'Antona, R. Tonlorenzi, M. A. Pellegrino, M. Meregalli   +16 more
core  

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

The Therapeutic Potential of Mesenchymal Stem Cells in Post-Stroke Depression. [PDF]

Int J Mol Sci
Fan M, Deng Q, Li Z, Wang G, Lu M.
europepmc   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source