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Stem cells offer the potential of new therapies for previously untreatable diseases. This session focuses on different aspects of stem cells from embryonic stem cells to adult stem cells and the biology and therapeutic impact of cancer stem cells.
L. Cheng+201 more
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Cells, Stem Cells, and Cancer Stem Cells [PDF]
The stem cell field owes a great deal to the previous work conducted by embryologists and researchers devoted to reproductive medicine. The time is coming when this emerging field will pay off in the reproductive sciences by offering new avenues of understanding gametogenesis and early embryonic development.
Carlos Simón+1 more
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Stem Cells and Stem Cell Therapy
Abstract This team-based learning (TBL) exercise presents hematopoietic malignancies of myeloid origin and invites users to consider appropriate methods of treatment utilizing stem cell therapy. The 100-minute session is structured in traditional TBL format, and all components—including the learning objectives, reading assignments, individual Readiness
Adam Gromley, Zeynep Gromley
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PTEN, Stem Cells, and Cancer Stem Cells [PDF]
Like normal stem cells, "cancer stem cells" have the capacity for indefinite proliferation and generation of new cancerous tissues through self-renewal and differentiation. Among the major intracellular signaling pathways, WNT, SHH, and NOTCH are known to be important in regulating normal stem cell activities, and their alterations are associated with ...
Hong Wu, Reginald Hill
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Stem Cells and Cancer Stem Cells [PDF]
The different organs in human organism are constituted by tissues with mature and specialized cells and its specific stem cells. Stem cells represent only a minuscule fraction of cells that constitute each tissue but they are the only cells with self-renewal capacity. The organ-specific stem cells have specific properties that maintain tissue integrity
Alfredo Ribeiro-Silva+2 more
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Prostate Stem Cells and Cancer Stem Cells [PDF]
Stem/progenitor cells play central roles in processes of organogenesis and tissue maintenance, whereas cancer stem cells (CSCs) are thought to drive tumor malignancy. Here, we review recent progress in the identification and analysis of normal prostate stem/progenitor cells as well as putative CSCs in both genetically engineered mouse models as well as
Michael M. Shen, Jia J. Li
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Glioblastomas are highly malignant primary brain tumors with one of the worst survival rates among all human cancers. With a more profound understanding of the cellular and molecular mechanisms of tumor initiation and acquired resistance to conventional radio- and chemotherapy, novel therapeutic targets might be discovered to optimize therapeutic ...
Tabatabai, G, Weller, M
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Stem cells: the intestinal stem cell as a paradigm [PDF]
Stem cell research provides a foundation for therapeutic advancement in oncology, clinical genetics and a diverse array of degenerative disorders. For example, the elucidation of pathways governing proliferative regulation and differentiation within cellular systems will result in medical strategies aimed at the root cause of cancer.
Andrew G Renehan+2 more
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The Stem Cells and the Cancer Stem Cells [PDF]
n ...
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Septins were first described in yeast. Due to extensive research in non-yeast cells, Septins are now recognized across all species as important players in the regulation of the cytoskeleton, in the establishment of polarity, for migration, vesicular trafficking and scaffolding.
Schuster, Tanja, Geiger, Hartmut
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