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Stem Cells and Stem Cell Therapy
Abstract This team-based learning (TBL) exercise presents hematopoietic malignancies of myeloid origin and invites users to consider appropriate methods of treatment utilizing stem cell therapy. The 100-minute session is structured in traditional TBL format, and all components—including the learning objectives, reading assignments, individual Readiness
Adam Gromley, Zeynep Gromley
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PTEN, Stem Cells, and Cancer Stem Cells [PDF]
Like normal stem cells, "cancer stem cells" have the capacity for indefinite proliferation and generation of new cancerous tissues through self-renewal and differentiation. Among the major intracellular signaling pathways, WNT, SHH, and NOTCH are known to be important in regulating normal stem cell activities, and their alterations are associated with ...
Hong Wu, Reginald Hill
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Stem Cells and Cancer Stem Cells [PDF]
The different organs in human organism are constituted by tissues with mature and specialized cells and its specific stem cells. Stem cells represent only a minuscule fraction of cells that constitute each tissue but they are the only cells with self-renewal capacity. The organ-specific stem cells have specific properties that maintain tissue integrity
Alfredo Ribeiro-Silva+2 more
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Stem cells of Hydra magnipapillata can differentiate into somatic cells and germ line cells [PDF]
We investigated whether all stem cells of Hydra can differentiate both somatic cells and gametes or if a separate germ line exists in these phylogenetically old organisms.
Bode+28 more
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Glioblastomas are highly malignant primary brain tumors with one of the worst survival rates among all human cancers. With a more profound understanding of the cellular and molecular mechanisms of tumor initiation and acquired resistance to conventional radio- and chemotherapy, novel therapeutic targets might be discovered to optimize therapeutic ...
Tabatabai, G, Weller, M
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Stem cells: the intestinal stem cell as a paradigm [PDF]
Stem cell research provides a foundation for therapeutic advancement in oncology, clinical genetics and a diverse array of degenerative disorders. For example, the elucidation of pathways governing proliferative regulation and differentiation within cellular systems will result in medical strategies aimed at the root cause of cancer.
Andrew G Renehan+2 more
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Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization. [PDF]
Implanted biomaterials and biomedical devices generally induce foreign body reaction and end up with encapsulation by a dense avascular fibrous layer enriched in extracellular matrix.
Chu, Julia+9 more
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Stem cell population asymmetry can reduce rate of replicative aging [PDF]
Cycling tissues such as the intestinal epithelium, germ line, and hair follicles, require a constant flux of differentiated cells. These tissues are maintained by a population of stem cells, which generate differentiated progenies and self-renew. Asymmetric division of each stem cell into one stem cell and one differentiated cell can accomplish both ...
arxiv +1 more source
The Stem Cells and the Cancer Stem Cells [PDF]
n ...
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Human stem cells and articular cartilage regeneration. [PDF]
The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki+2 more
core +4 more sources