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SHED: Stem Cells From Human Exfoliated Deciduous Teeth [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2003
To isolate high-quality human postnatal stem cells from accessible resources is an important goal for stem-cell research. In this study we found that exfoliated human deciduous tooth contains multipotent stem cells [ s tem cells from h uman
Bai Lu, Songtao Shi, Pamela Robey
exaly   +4 more sources

Stem Cells From Human Exfoliated Deciduous Teeth: A Concise Review

Current Stem Cell Research and Therapy, 2020
Stem Cells from Human Exfoliated Deciduous Teeth (SHED) originate from the embryonic neural crest as ectodermal mesenchymal stem cells and are isolated from human deciduous teeth. SHED expresses the same cell markers as Embryonic Stem Cells (ESCs), such as OCT4 and NANOG, which make SHED to have a significant impact on clinical applications.
Wen-Ta Su, Jen-Hao Chen
exaly   +3 more sources

Characteristics of Stem Cells From Human Exfoliated Deciduous Teeth (SHED) From Intact Cryopreserved Deciduous Teeth

open access: yesCryobiology, 2015
The aim of this study is to compare the characteristics of stem cells derived from human exfoliated deciduous teeth (SHED) from cryopreserved intact deciduous teeth with those of fresh SHED. In total, 20 exfoliated deciduous teeth were randomly divided into a fresh group (f-SHED; n = 11) and cryopreserved group (c-SHED; n = 9; stored for 1-8 months ...
Hyo-Seol Lee, Je Seon Song, Jae-Ho Lee
exaly   +4 more sources

Comparative Characterization of Stem Cells From Human Exfoliated Deciduous Teeth and Dental Pulp Stem Cells

Archives of Oral Biology, 2012
This study focused on the characterization of stem cells from human exfoliated deciduous teeth (SHED) in comparison with dental pulp stem cells (DPSCs) to certify SHED as a key element in tissue engineering.In the present study, SHED and DPSCs were assayed for their cell surface antigens and proliferation by measuring the cell cycles, growth rates ...
Kun Xuan, Guang-Hui Li, Kun Ji
exaly   +3 more sources

Stem Cells from Human Exfoliated Deciduous Teeth: A Growing Literature

Cells Tissues Organs, 2016
Adult stem cells research has been considered the most advanced sort of medical-scientific research, particularly stem cells from human exfoliated deciduous teeth (SHED), which represent an immature stem cell population. The purpose of this review is to describe the current knowledge concerning SHED from full-text scientific publications from 2003 to ...
Daniel, Martinez Saez   +3 more
openaire   +2 more sources

Single-Cell Sorting of Immunophenotyped Mesenchymal Stem Cells from Human Exfoliated Deciduous Teeth

Journal of Visualized Experiments, 2023
The mesenchymal stem cells (MSCs) of an organism possess an extraordinary capacity to differentiate into multiple lineages of adult cells in the body and are known for their immunomodulatory and anti-inflammatory properties. The use of these stem cells is a boon to the field of regenerative biology, but at the same time, a bane to regenerative medicine
Ayona, Gupta   +4 more
openaire   +2 more sources

Hedgehog signalling is dispensable in the proliferation of stem cells from human exfoliated deciduous teeth

Cell Biology International, 2014
AbstractThe hedgehog (Hh) signalling pathway is one of the key regulators in development with a dual role in cell fate specification, proliferation, and survival on different target cells. We have investigated the effect of recombinant sonic hedgehog (r‐SHH) on extracted multipotent stem cells from human exfoliated deciduous teeth (SHED), which ...
Fatemeh, Ejeian   +2 more
openaire   +2 more sources

Effect of a cryopreservation protocol on the proliferation of stem cells from human exfoliated deciduous teeth

Acta Odontologica Scandinavica, 2016
The aim of the present study was to evaluate the influence of a cryopreservation protocol on the proliferation and viability of stem cells from human exfoliated deciduous teeth (SHEDs).Cells from the pulp of three deciduous teeth were isolated and characterized to confirm their stem cell nature.
Fernanda, Ginani   +5 more
openaire   +2 more sources

Banking Stem Cells from Human Exfoliated Deciduous Teeth (SHED): Saving for the Future

Journal of Clinical Pediatric Dentistry, 2009
Tooth derived cells are readily accessible and provide an easy and minimally invasive way to obtain and store stem cells for future use. Banking ones own tooth-derived stem cells is a reasonable and simple alternative to harvesting stem cells from other tissues.Obtaining stem cells from human exfoliated deciduous teeth (SHED) is simple and convenient ...
Vipin, Arora, Pooja, Arora, A K, Munshi
openaire   +2 more sources

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