Results 171 to 180 of about 69,259,824 (258)

Naive Embryonic Stem Cells: The Future of Stem Cell Research? [PDF]

Regenerative Medicine, 2014
openaire   +2 more sources

Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons [PDF]

Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to NeuronsAbstract Background and Objectives: Hair Follicle Bulge region due to its availability and abundance is one of the areas which is easily accessible to Multi-potent
آسالگو, سارا, کردستانی شرق, بهاره, نوبخت, ملیحه, رهبر روشندل, ناهید, نجف زاده, نوروز, موسوی زاده, کاظم   +5 more
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Current Issues and Regulations in Tendon Regeneration and Musculoskeletal Repair with Mesenchymal Stem Cells

, 2011
Mesenchymal stem cells are multipotent stromal cells residing within the connective tissue of most organs. Their surface phenotype has been well described.
Grange, Simon
core  

Plasticity in growth behavior of patients' acute myeloid leukemia stem cells growing in mice

Haematologica, 2020
Sarah Ebinger, Christina Zeller, Michela Carlet, Daniela Senft, Johannes W. Bagnoli, Wen-Hsin Liu, Maja Rothenberg-Thurley, Wolfgang Enard, Klaus H. Metzeler, Tobias Herold, Karsten Spiekermann, Binje Vick, Irmela Jeremias   +12 more
doaj   +1 more source

P1336: LONGTERM EX VIVO EXPANSION OF FUNCTIONAL MURINE AND HUMAN HEMATOPOIETIC STEM CELLS USING BONE-LINING STROMAL CELLS

HemaSphere, 2023
Lukas Klein, Shubhankar Sood, Franziska Pilz, Pit Albert, Ramon Barrull Mascaró, Sonia Fernandez Torices, Nanni Schmitt, Daniel Nowak, Marieke Essers   +8 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source