Results 61 to 70 of about 1,076,552 (304)

STEM Education Fiscal Year 2015: An Analysis of Educational Investments and Expectations [PDF]

open access: yes, 2016
In his Fiscal Year 2015 budget, President Obama proposed a strengthened investment in education with particular emphasis on STEM. With a $600.1 million budget, the President proposed several initiatives directed primarily at pre-Kindergarten through ...
Ernst, Jeremy V., Swaby, Keri
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Addressing the need to facilitate undergraduate research experiences for community college transfer students in science

open access: yesJournal of Microbiology & Biology Education
Community college transfer students face numerous challenges, including gaining access to undergraduate research experiences. In this Perspectives piece, we articulate the benefits of undergraduate research experiences for community college transfer ...
Emma C. Goodwin   +3 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

The U.S. Science and Technology Workforce [PDF]

open access: yes, 2008
[Excerpt] In the 21st century, global competition and rapid advances in science and technology will challenge the scientific and technical proficiency of the U.S. workforce.
Matthews, Christine M, Stine, Deborah D
core   +6 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Relationship between the cognitive load and the learning success in applying force diagrams: eye-tracking study

open access: yesFrontiers in Education
IntroductionThis paper is concerned with investigating the cognitive demands of solving force diagram tasks in different scenarios, specifically in the wind context.MethodsIn this study, students were trained using worked examples and then completed ...
Yultuz Omarbakiyeva   +5 more
doaj   +1 more source

THE ROLE OF STEM EDUCATION IN THE PROFESSIONAL TRAINING OF FUTURE SPECIALISTS IN ENGINEERING AND PEDAGOGICAL FIELDS [PDF]

open access: yesAlfred Nobel University Journal of Pedagogy and Psychology
The article is devoted to analysing the implementation of STEM education in higher education institu- tions, aiming to develop competencies in future specialists in engineering and pedagogical fields necessary for effective activity in the context of ...
Tarasov Volodymyr, Tyutyunov Oleg
doaj   +1 more source

Principles And Practices Fostering Inclusive Excellence: Lessons From The Howard Hughes Medical Institute’s Capstone Institutions [PDF]

open access: yes, 2016
Best-practices pedagogy in science, technology, engineering, and mathematics (STEM) aims for inclusive excellence that fosters student persistence. This paper describes principles of inclusivity across 11 primarily undergraduate institutions designated ...
Cooke, D. B., III   +15 more
core   +6 more sources

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