Results 71 to 80 of about 978,649 (302)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Identification of Key Genes of Fruit Shape Variation in Jujube with Integrating Elliptic Fourier Descriptors and Transcriptome

Plants
Jujube (Ziziphus jujuba) exhibits a rich diversity in fruit shape, with natural occurrences of gourd-like, flattened, and other special shapes. Despite the ongoing research into fruit shape, studies integrating elliptical Fourier descriptors (EFDs) with ...
Yue Ren, Wenqing Fu, Yi Gao, Yuhan Chen, Decang Kong, Ming Cao, Xiaoming Pang, Wenhao Bo   +7 more
doaj   +1 more source

Initial Rotational Instability of the Tapered Wedge-Shaped Type Cementless Stem

Advances in Orthopedics, 2020
Background. Because the tapered wedge-shaped type cementless stem has a small anteroposterior width and a low occupation rate in the medullary space, postoperative rotational instability and stem subsidence due to inadequate proximal fixation are ...
Yosuke Iwamoto, Hiroaki Kijima, Hiroshi Tazawa, Natsuo Konishi, Hitoshi Kubota, Shin Yamada, Takayuki Tani, Keiji Kamo, Norio Suzuki, Yoshihiko Okudera, Masashi Fujii, Ken Sasaki, Tetsuya Kawano, Itsuki Nagahata, Naohisa Miyakoshi, Yoichi Shimada   +15 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Anatomical studies of leaf and stem on Ornithogalum (Hyacinthaceae) in Iran

تاکسونومی و بیوسیستماتیک, 2013
In this study, leaf and stem (scape) anatomy of 11 species of the genus Ornithogalum (Hyacinthaceae) in Iran were studied. Plant samples were collected and then fixed and handmade cross-sections of leave were prepared and stained with methyl green and ...
Taher Nejadsattari, Seyed Mohammad Mehdi Hamdi, Fatemeh Heidarian, Mostafa Assadi   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Similar effect of stem geometry on radiological changes with 2 types of cemented straight stem: The Müller stem and the Virtec stem compared in 711 hips

Acta Orthopaedica, 2016
Background and purpose — There are 2 basic principles in cemented stem fixation: shape-closed and force-closed. We investigated 2 shape-closed straight stems, the Müller (MSS) and the Virtec (VSS), which differ only in geometrical cross section, to ...
Martin Clauss, Lilianna Bolliger, Daniel Brandenberger, Peter E Ochsner, Thomas Ilchmann   +4 more
doaj   +1 more source

Shape of Scots pine knots close to the stem pith.

Silva Fennica, 1989
The shape of Scots pine ( L.) knots close to the pith of butt logs was investigated. 1,100 knots were split in a vertical direction, and their shape was measured.
Pietilä, Jukka
doaj   +1 more source