Results 81 to 90 of about 978,649 (302)

Equilibrium rotation of a vortex bundle terminating on a lateral wall

open access: yes, 2011
The paper investigates possibility of equilibrium solid-body rotation of a vortex bundle diverging at some height from a cylinder axis and terminating on a lateral wall of a container.
E. B. Sonin   +7 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

High-throughput continuous dielectrophoretic separation of neural stem cells. [PDF]

open access: yes, 2019
We created an integrated microfluidic cell separation system that incorporates hydrophoresis and dielectrophoresis modules to facilitate high-throughput continuous cell separation. The hydrophoresis module consists of a serpentine channel with ridges and
Adams, Tayloria NG   +6 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Finite element analysis part 1 of 2: Influence of short stem implant polyethylene configuration on glenohumeral joint biomechanics

open access: yesJournal of Experimental Orthopaedics
Purpose Stress shielding in short‐stem arthroplasty can cause critical metaphyseal bone loss. If the size and shape of the humeral shaft are important factors, it is unknown whether the shape of the polyethylene component in reverse shoulder arthroplasty
Geoffroy Nourissat   +5 more
doaj   +1 more source

STEM observation of a multiphase nucleus of spheroidal graphite

open access: yesJournal of Materials Research and Technology, 2020
As part of a study on nucleation and growth of graphite in spheroidal graphite irons, systematic transmission electron microscopy observations are carried out.
Lydia Laffont   +3 more
doaj   +1 more source

Two new species of Antarctic gorgonians (Octocorallia: Primnoidae) with a redescription of Thouarella laxa Versluys, 1906 [PDF]

open access: yes, 2009
Two new species of the genus Thouarella from Antarctic waters are described and illustrated from material collected on the Polarstern cruises ANT XVII/3 (EASIZ III), ANT XIX/5 (LAMPOS) and ANT XXI/2 (BENDEX).
López González, Pablo José   +1 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

PATTERNA: transcriptome-wide search for functional RNA elements via structural data signatures. [PDF]

open access: yes, 2018
Establishing a link between RNA structure and function remains a great challenge in RNA biology. The emergence of high-throughput structure profiling experiments is revolutionizing our ability to decipher structure, yet principled approaches for ...
Aviran, Sharon, Ledda, Mirko
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Home - About - Disclaimer - Privacy