Results 91 to 100 of about 12,197 (302)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Recent Advances in Stepped Spillway Design: Air-Water Flow on Stepped Chutes, Embankment Dam Stepped Spillway and Other Considerations [PDF]

open access: yes, 2004
New experiments were conducted in a large stepped channel with a 22 degree slope operating at large Reynolds numbers. Interactions between free-surface and cavity recirculation were systematically investigated in the skimming flow regime.
Chanson, H., Gonzalez, C. A.
core  

Aeration and air-water mass transfer on stepped chutes with embankment dam slopes [PDF]

open access: yes, 2015
Stepped spillway flows are characterised by significant free-surface aeration downstream of the inception point of air entrainment. The stepped design is advantageous for applications which require large energy dissipation and strong flow aeration. While
Chanson, Hubert   +3 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

A Mechanism for TiO2 Formation on Stepped TiN (001) from First-Principles Calculations

open access: yes, 2014
The adsorption of O-2 on the TiN(001) stepped surface and the consequent formation of surface oxide have been characterized using first-principles calculations. The adsorption and dissociation of O-2 on both the flat and the stepped surface are predicted
Sinnott, Susan B.   +7 more
core   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Experimental investigation of time-dependent local scour downstream of a stepped channel

open access: yes, 2019
In this study, temporal variation of local scour occurring at the downstream part of the stepped channel were investigated experimentally. The experimental tests were carried out in a stepped flume with a height of 2.4 m.
Aksoy, Aysegul Ozgenc   +2 more
core   +1 more source

Influence of Stepped Boulder Array on Flow Structure in Mountain River

open access: yes工程科学与技术, 2018
Stepped boulder arrays induced by flash flood are common riverbed forms in mountainous areas,and they can greatly affect the river flow structure and bed transformation.Although boulder arrays increase flow and river erosion resistance,they also ...
Chen YE   +4 more
doaj  

A retrogressive erosion model with automatic adjustment for sediment entrainment dominated and mass failure dominated bed deformation

open access: yesInternational Journal of Sediment Research
Retrogressive erosion, a critical process impacting river engineering structures, channel geomorphology, and reservoir sediment management, manifests primarily in two distinct forms: rotating and stepped bed deformation.
Zenghui Wang   +4 more
doaj   +1 more source

A Compact Low-Power LoRa IoT Sensor Node with Extended Dynamic Range for Channel Measurements

open access: yesSensors, 2018
As sub-GHz wireless Internet of Things (IoT) sensor networks set the stage for long-range, low-data-rate communication, wireless technologies such as LoRa and SigFox receive a lot of attention.
Thomas Ameloot   +2 more
doaj   +1 more source

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