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International Journal of Peptide and Protein Research, 1988
This review article, based on a lecture delivered in Madras in 1985, is an account of the author's experience in the working out of the molecular structure and conformation of the collagen triple‐helix over the years 1952–78. It starts with the first proposal of the correct triple‐helix in 1954, but with three residues per turn, which was later refined
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This review article, based on a lecture delivered in Madras in 1985, is an account of the author's experience in the working out of the molecular structure and conformation of the collagen triple‐helix over the years 1952–78. It starts with the first proposal of the correct triple‐helix in 1954, but with three residues per turn, which was later refined
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Stereochemistry in subcomponent self-assembly.
Accounts of Chemical Research, 2014CONSPECTUS: As Pasteur noted more than 150 years ago, asymmetry exists in matter at all organization levels. Biopolymers such as proteins or DNA adopt one-handed conformations, as a result of the chirality of their constituent building blocks.
A. Castilla, W. Ramsay, J. Nitschke
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Evaluating Ketoreductase Exchanges as a Means of Rationally Altering Polyketide Stereochemistry
ChemBioChem, 2015Modular polyketide synthases (PKSs) are multidomain multienzymes responsible for the biosynthesis in bacteria of a wide range of polyketide secondary metabolites of clinical value.
T. Annaval+4 more
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Journal of Organic Chemistry, 2015
The publication in January 1965 of the first Woodward–Hoffmann paper, The Stereochemistry of Electrocyclic Reactions, ushered into organic chemistry both an explanation of the stereochemistry and “allowedness” or “forbiddenness” of concerted reactions ...
J. I. Seeman
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The publication in January 1965 of the first Woodward–Hoffmann paper, The Stereochemistry of Electrocyclic Reactions, ushered into organic chemistry both an explanation of the stereochemistry and “allowedness” or “forbiddenness” of concerted reactions ...
J. I. Seeman
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Organic Stereochemistry: Experimental and Computational Methods
, 2015The text is clearly divided into three sections on fundamentals, spectroscopic and computational techniques, and applications in organic synthesis. The first part provides a brief introduction to the field of chirality and stereochemistry, while the ...
Hua-Jie Zhu
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Enhancing the Magnitude of Antibody Responses through Biomaterial Stereochemistry.
ACS Biomaterials Science & Engineering, 2015d-Amino acid analogs of peptides and proteins are attractive for applications in biotechnology and medicine due to their reduced proteolytic sensitivity.
Rajagopal Appavu+6 more
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CO2 copolymers from epoxides: catalyst activity, product selectivity, and stereochemistry control.
Accounts of Chemical Research, 2012The use of carbon dioxide as a carbon source for the synthesis of organic chemicals can contribute to a more sustainable chemical industry. Because CO(2) is such a thermodynamically stable molecule, few effective catalysts are available to facilitate ...
Xiao‐Bing Lu, Wei-Min Ren, Guang Wu
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Antibacterial adhesion of borneol-based polymer via surface chiral stereochemistry.
ACS Applied Materials and Interfaces, 2014During its adhesion on external surfaces, a cell exhibits obvious inclination to different molecular chirality, which encourages us to develop a new type of antibacterial material catering to the "chiral taste" of bacteria.
Lingqiong Luo+5 more
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Stereochemistry and Bioequivalence
The Journal of Clinical Pharmacology, 1992Despite the fact that many important drugs are chiral, for a variety of reasons they are marketed as racemates (i.e., an equal proportion of two enantiomers). Although enantiomers of racemic drugs often differ from one another in their pharmacodynamic and pharmacokinetic properties, bioequivalence assessments are made using nonstereospecific assays ...
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