Results 61 to 70 of about 40,087 (250)
Borylcyclopropanes: Synthetic Strategies and Applications
Angewandte Chemie, EarlyView.Borylcyclopropanes (cyclopropanes bearing a boron substituent) sit at the intersection of two privileged frameworks in synthesis. This review provides the first exhaustive survey of their chemistry, spanning metal–carbene, nucleophilic cyclization, radical, hydroboration, and C─H activation routes, and documenting applications in medicinal chemistry ...
Aiza A. Butt, Joseph M. Ready
wiley +2 more sources
Crystal structure of 9-methacryloylanthracene
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C18H14O, with systematic name 1-(anthracen-9-yl)-2-methylprop-2-en-1-one, the ketonic C atom lies 0.2030 (16) Å out of the anthryl-ring-system plane. The dihedral angle between the planes of the anthryl and methacryloyl moieties is
Aditya Agrahari +4 more
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Angewandte Chemie, EarlyView.A stereoselective functionalization method of cyclic imines under mild organocatalytic conditions was developed. Bifunctional cinchona alkaloid catalysts combined with carefully optimized reaction conditions to suppress background reactivity enabled highly enantio‐ and diastereoselective addition reactions of malonates to cyclic imines.
Frederic Kölblin, Helma Wennemers
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Angewandte Chemie, EarlyView.Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch +4 more
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Five-membered ring annelation in [2.2]paracyclophanes by aldol condensation
Beilstein Journal of Organic Chemistry, 2014 Under basic conditions 4,5,12,13-tetraacetyl[2.2]paracyclophane (9) cyclizes by a double aldol condensation to provide the two aldols 12 and 15 in a 3:7 ratio.
Henning Hopf +2 more
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Cobalt‐Catalyzed Radical Ligand Transfer (RLT) Enables Remote‐Markovnikov Hydroamination of Alkenes
Angewandte Chemie, EarlyView.A cobalt‐catalyzed remote‐Markovnikov 1,3‐hydroamination of allyl carboxylates proceeds through MHAT, 1,2‐radical acyloxy migration (1,2‐RAM), and radical ligand transfer (RLT) from a Co‐N intermediate, providing protected amino alcohols. ABSTRACT Amino alcohols are prevalent in pharmaceuticals, agrochemicals, and functional materials, yet ...
Arman Khosravi +7 more
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Unbiased Structure Prediction of Sophisticated Cage Structures
Angewandte Chemie, EarlyView.We introduce the software and workflow for automated, unbiased exploration of all possible connectivities of a given set of building blocks and their stoichiometry to predict stable cage structures. ABSTRACT Cage structure prediction has made significant strides by generating structures based on what the community has seen before.
Andrew Tarzia, Giovanni M. Pavan
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Angewandte Chemie, EarlyView.A nickel‐catalyzed C–C cross‐coupling protocol employing bench‐stable glycosyl sulfonyl hydrazides as practical glycosyl radical precursors is reported. A variety of (hetero)aryl iodides underwent cross‐coupling under redox‐neutral conditions to afford structurally diverse unprotected C‐(hetero)aryl glycosides.
Cai‐Ming Wang +3 more
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Contribution of the Chemistry Institutes to the Early Development of Stereochemistry
CHIMIA, 2009 This article is a translation from German of a paper submitted by Kurt Hermann to the University of Zurich Prize committee in 1968, with additional editing by Jay Siegel.
Kurt Hermann
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