Results 81 to 90 of about 40,087 (250)

Stereochemical course of hydrolytic reaction catalyzed by alpha-galactosidase from cold adaptable marine bacterium of genus Pseudoalteromonas

Frontiers in Chemistry, 2014
The recombinant α-galactosidase of the marine bacterium (α-PsGal) was synthesized with the use of the plasmid 40Gal, consisting of plasmid pET-40b (+) (Novagen) and the gene corresponding to the open reading frame of the mature α-galactosidase of marine ...
Irina Yu Bakunina, Larissa A Balabanova, Vasiliy A Golotin, Lyubov V Slepchenko, Lyubov V Slepchenko, Vladimir V Isakov, Valeriy A Rasskazov   +6 more
doaj   +1 more source

THE STEREOCHEMISTRY OF FUMAGILLIN [PDF]

Proceedings of the National Academy of Sciences, 1962
J R, Turner, D S, Tarbell
openaire   +2 more sources

A Two-Layer Structural Key Framework for Linking Compound Identifiers and MS/MS Evidence in Spectral Database Curation

Metabolites
Background: MS/MS spectral databases provide reference spectra for compound identification in metabolomics studies. Their utility depends on clear links among compound identifiers, chemical structures, and MS/MS evidence, yet these links are often ...
Kaiwen Deng, Ran Liu, Ruiping He, Li Chen   +3 more
doaj   +1 more source

Survey of Pharmacological Activity and Pharmacokinetics of Selected β-Adrenergic Blockers in Regard to Their Stereochemistry

Applied Sciences, 2019
The present survey concentrates on pharmacodynamics and pharmacokinetics of selected β-adrenergic blockers from the point of view of their stereochemistry. It could be shown that the activity in the arylaminoethanol and aryloxyaminopropanol group of
Ružena Čižmáriková, Ladislav Habala, Jindra Valentová, Mário Markuliak   +3 more
doaj   +1 more source

Regio- and stereochemical stability induced by anomeric and gauche effects in difluorinated pyrrolidines

Beilstein Journal of Organic Chemistry
Selective fluorination of the pyrrolidine ring in proline motifs has been found to induce significant conformational changes that impact the structure and biological roles of modified peptides and proteins.
Ana Flávia Candida Silva, Francisco A. Martins, Matheus P. Freitas   +2 more
doaj   +1 more source

Preparation of spirocyclic oxindoles by cyclisation of an oxime to a nitrone and dipolar cycloaddition

Beilstein Journal of Organic Chemistry
Oxindoles are an important class of compounds with significant biological activities. Spirocyclic derivatives are present in a variety of natural products.
Beth L. Ritchie, Alexandra Longcake, Iain Coldham   +2 more
doaj   +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, EarlyView.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Stereochemistry of (—)-Vertinolide [PDF]

Agricultural and Biological Chemistry, 1983
TAKAIWA, Akihiro, YAMASHITA, Kyohei
openaire   +2 more sources

General Anesthetics: Aspects of Chirality, Pharmacodynamics, and Pharmacokinetics

Pharmaceuticals
The introduction of general anesthetics in the mid-19th century is considered one of the greatest contributions to medical practice. It was the first time that complicated surgical interventions became feasible, without putting an excessive strain on the
Ružena Čižmáriková, Ladislav Habala, Jindra Valentová   +2 more
doaj   +1 more source

The Stereochemistry of Dihydrolycorine.

Pharmaceutical Bulletin, 1957
Takeda, Kenichi, Kotera, Katsumi
openaire   +3 more sources