Results 81 to 90 of about 15,265 (249)

A General Strategy for the Synthesis of Jerangolids Enabled by π‐allyl Stille Coupling

Chemistry – A European Journal, EarlyView.
A general strategy for the synthesis of jerangolids is established, featuring a late‐stage π‐allyl Stille coupling of two advanced, highly customizable building blocks to form the skipped diene core. The approach provides access to all naturally occurring jerangolids, including jerangolid H, whose configuration is confirmed by NMR analysis.
Janick Schug, Bernd Morgenstern, Johann Jauch   +2 more
wiley   +1 more source

Benzo[cd]azulenyl: A Structural Isomer of Phenalenyl—Synthesis and Properties of Its Tri‐tert‐butyl‐substituted Derivative and Formation of a Thermal‐ and Photoresponsive σ‐Dimer

Chemistry – A European Journal, EarlyView.
Benzo[cd]azulenyl, a nonalternant isomer of phenalenyl, is identified as a new member of the nonalternant hydrocarbon radical family. The tri‐tert‐butyl substituted derivative forms a stable σ‐dimer in the solid state. Upon exposure to external stimuli such as light and heat, the σ‐bond of the dimer dissociates, producing the monomeric radical.
Kaho Takeuchi, Akihito Konishi, Makoto Yasuda   +2 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Guanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral pain [PDF]

, 2014
Activation of guanylate cyclase-C (GC-C) expressed predominantly on intestinal epithelial cells by guanylin, uroguanylin or the closely related GC-C agonist peptide, linaclotide, stimulates generation and release of cyclic guanosine-3’,5’-monophosphate (
Alexander P. Bryant, Boris Tchernychev, Caroline B. Kurtz, Gerhard Hannig, Inmaculada Silos-Santiago, Mark G. Currie   +5 more
core   +2 more sources

Electrochemically Driven Domino Nucleophilic Addition/Diels–Alder Reaction: From 2‐Aminophenol Derivatives to Bridged Tricyclic Systems

European Journal of Organic Chemistry, EarlyView.
This electrochemical methodology allows the preparation of bridged tricyclic scaffolds through a rapid increase in the molecular complexity of simple and readily accessible starting materials. Alcohols proved to be the most efficient nucleophiles, as well as 6‐chloropurine. Plausibly, the process involves an anodic oxidative dearomatization to generate
Emanuele Cartamina, Sara Colombo, Davide Spanu, Gianluigi Broggini, Camilla Loro   +4 more
wiley   +1 more source

Stereoisomeric engineering mediated zinc metal electrodeposition: Critical balance of solvation and adsorption capability

Advanced Powder Materials
The exceptional electrochemical performance of zinc anodes is frequently impeded by inadequate deposition kinetics and interfacial chemistry. Herein, we introduce the stereoisomerism to inform the balanced selection of electrolyte additives, taking into ...
Wen Liu, Qiwen Zhao, Ruheng Jiang, Xuyan Ni, Tiancheng You, Canglong Li, Yanzi Deng, Bingang Xu, Yuejiao Chen, Libao Chen   +9 more
doaj   +1 more source

planar stereoisomerism

, 2019
Citation: 'planar stereoisomerism' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04684 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

A Practical and Flexible De Novo Synthesis of Deoxygenated Carbasugars and Their Cyclitol Epoxides

European Journal of Organic Chemistry, EarlyView.
A de novo synthesis route comprising enantioselective Brown crotylation and ring‐closing metathesis as the key steps enables the synthesis of a‐ and b‐carba‐paratose, a‐ and b‐carba‐colitose as well as four configurational deoxycyclophellitol isosteres.
Yevhenii Radchenko, Nick D. F. Puijmbroeck, Sanne M. Verduin, Jeroen D. C. Codée, Herman S. Overkleeft   +4 more
wiley   +1 more source

Alkali cation-π interactions in aqueous systems, modulating supramolecular stereoisomerism of nanoscopic metal-organic capsules

Nature Communications
Contrary to common chemical intuition, cation-π interactions can persist in polar, aqueous reaction solutions, rather than in dry non-coordinative solvent systems.
Paul Wix, Swetanshu Tandon, Sebastien Vaesen, Kadri Karimu, Jennifer S. Mathieson, Kane Esien, Solveig Felton, Graeme W. Watson, Wolfgang Schmitt   +8 more
doaj   +1 more source

As nove premissas anestesiológicas da Bíblia Las nueve premisas anestesiológicas de la Biblia Nine Biblical anesthetic premises

Revista Brasileira de Anestesiologia, 2003
JUSTIFICATIVA E OBJETIVOS: Os autores fazem uma análise histórica de nove premissas inerentes à prática anestésica que já estão referenciadas na Bíblia há mais de 3.000 anos (Velho Testamento).
Nilton Bezerra do Vale, José Delfino
doaj   +1 more source