Results 61 to 70 of about 13,428 (198)

Cellular Membrane‐Targeted Europium(III) Probe for Selective and Time‐Resolved Detection of Peroxynitrite

Chemistry – A European Journal, EarlyView.
We report a cellular membrane‐targeted europium(III) probe, Eu.Chol, that enables selective, time‐resolved detection of peroxynitrite (ONOO−) at the cell membrane interface. Eu.Chol demonstrates efficient incorporation into liposomes and Jurkat cells, with minimal response to H2O2, establishing a modular platform for subcellular ONOO− sensing ...
Jamie Webb, Rebecca Tiffany, Karolis Norvaisa, Hennie Valkenier, Lea Miebach, Sander Bekeschus, Stephen J. Butler   +6 more
wiley   +1 more source

THE STRUCTURE AND CONFORMATION OF LIGNIN AS JUDGED BY X-RAY CRYSTALLOGRAPHIC INVESTIGATIONS OF LIGNIN MODEL COMPOUNDS: ARYLGLYCEROL -SYRINGYL ETHERS

BioResources, 2009
Structural elements of the arylglycerol -syringyl ether type are very frequent in hardwood lignins. A variety of crystalline dimeric lignin models representing different diastereomeric forms of structural elements in lignin of this type have been ...
Knut Lundquist, Vratislav Langer, Jim Parkås   +2 more
doaj  

N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines

Chemistry – A European Journal, EarlyView.
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga, Jérôme Marrot, Ana Poveda, Nicolas Auberger, Jesús Jiménez‐Barbero, Jérôme Désiré, Yves Blériot   +6 more
wiley   +1 more source

Marine algae and their bioactive compounds as novel modulators for mitochondrial quality control: from mechanism to therapeutic potential

Frontiers in Marine Science
Mitochondrial Quality Control (MQC) is the core mechanism for ensuring mitochondrial quality and maintaining cellular function. Marine algae and their bioactive compounds represent a huge treasure trove of natural medicines.
Chi Zhang, Ling Yuan, Jingjing Li, Doudou Lu, Yuhua Du, Yi Nan   +5 more
doaj   +1 more source

Lanthanide Centered and Circular Polarized Luminescence (CPL) From Tb(III) Complexes Made From Structurally Simple Methoxy‐Phenyl and Phenol‐Derived Pyridyldiamide (pda) Ligands

Chemistry – A European Journal, EarlyView.
The development of chiral pda derived methoxy ligands L1a [1(R,R)] and L1b [1(S,S)], along with their phenol derivatives L2a [2(R,R)] and L2b [2(S,S)], and their respective Tb(III) complexes is described. These Tb‐complexes exhibited Tb(III)‐centered emission upon and their chiroptical properties were probed by using both CD and CPL spectroscopy ...
Jennifer E. Jones, Jonathan A. Kitchen, Robert D. Peacock, Thorfinnur Gunnlaugsson   +3 more
wiley   +1 more source

Phosphanyl Radicals From Bismuth‐Mediated Reactions and Sterically Encumbered Diphosphanes

Chemistry – A European Journal, EarlyView.
Reactions of LiPR2 with BiCl3 selectively give diphosphanes R2P–PR2 in high yields, presumably via Bi─P homolysis. This includes challenging cases with bulky substituents R. Sterically encumbered diphosphanes release persistent phosphanyl radicals [PR2]• in thermally initiated equilibrium reactions.
Sascha Reith, Marius Junghanns, Felix Möller, Crispin Lichtenberg   +3 more
wiley   +1 more source

Characterization and design of dipeptide media formulation for scalable therapeutic production

Applied Microbiology and Biotechnology
Process intensification and simplification in biopharmaceutical manufacturing have driven the exploration of advanced feeding strategies to improve culture performance and process consistency.
Jinsung Song, Seo-Young Park, Dong-Yup Lee   +2 more
doaj   +1 more source

Computational insights into the stereo-selectivity of catechins for the inhibition of the cancer therapeutic target EGFR kinase

Frontiers in Pharmacology
The epidermal growth factor receptor (EGFR) plays a crucial role in regulating cellular growth and survival, and its dysregulation is implicated in various cancers, making it a prime target for cancer therapy.
Mohd Rehan, Mohd Rehan, Firoz Ahmed, Firoz Ahmed, Mohammad Imran Khan, Hifzur Rahman Ansari, Shazi Shakil, Shazi Shakil, Shazi Shakil, Moustafa E. El-Araby, Salman Hosawi, Mohammad Saleem, Mohammad Saleem   +12 more
doaj   +1 more source

Tribenzotriquinacene Fused Dimers (“Fusodimers”)—Synthesis and Host–Guest Properties

Chemistry – A European Journal, EarlyView.
Two tribenzotriquinacene units merged with each other in either syn‐ or anti‐orientation of the bowls have become accessible in a short synthesis. In contrast to the anti‐isomer, the syn‐isomer forms 1:1 host–guest complexes with both C60 and C70 in solution and in the solid state, as shown by 1H NMR spectroscopy and x‐ray diffraction.
Chun‐Fai Ng, Lisi He, Yin‐Ying Cheung, Xiao‐Ping Cao, Dietmar Kuck, Hak‐Fun Chow   +5 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source