Results 51 to 60 of about 13,728 (257)
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa +8 more
wiley +1 more source
The unique monomer and excimer fluorescence emissions of pyrene were first exploited as distinctly photophysical signals to identify the possible diastereomers of guests within nor-seco-cucurbit[10]uril (NS-CB[10]) cavities.
Xiaodong Zhang +3 more
doaj +1 more source
Scientific Opinion on Flavouring Group Evaluation 82, Revision 1 (FGE.82Rev1): Consideration of Epoxides evaluated by the JECFA (65th meeting) [PDF]
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan +13 more
wiley +1 more source
Purpose: studying seasonal periodicity of stereoisomerism of uteroplacental complex, the dynamics of body weight of infants, studying the chronostructure of mezorhythms of contractive activity of right and left parts of the uterus.Material and Methods ...
N. A. Rogova +4 more
doaj +1 more source
Stereoisomere Phenylbrommilchsäuren [PDF]
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Erlenmeyer, E., Moebes, A.
openaire +2 more sources
A nickel‐free and practical synthesis strategy to poly(pyrene tetraone) and its integration with a percolated CNTs/Ketjen Black network enables stable cycling and efficient energy storage in a sodium‐based batteries. This work demonstrates how controlling polymer structure and electrode architecture improves ion transport and mitigates dissolution in ...
Md. Adil +9 more
wiley +1 more source
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng +4 more
wiley +1 more source
Anti-atherosclerotic activity of catechins depends on their stereoisomerism
In terms of stereochemistry, catechins are divided into two groups: (-) epi forms (2R, 3R) and (-) forms (2S, 3R). Most of the catechins present in green tea are (-) epi forms (2R, 3R).
Maślak, Edyta +4 more
core +1 more source
The static stereoisomerism of bis- and tris-triaryl systems has been analyzed by a systematic stereochemical analysis, and the resulting theoretical predictions have been experimentally confirmed by using reversed-phase HPLC and ESR and 1H NMR ...
Josep Sedó (2955072) +5 more
core +1 more source

